Western Blot (WB)
(KLF2 Antibody (N-term) (MBS9205028) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).)
Rabbit anti-Human, mouse KLF2 Polyclonal Antibody | anti-KLF2 antibody
KLF2 Antibody (N-term)
Western Blot (WB)
(KLF2 Antibody (N-term) (MBS9205028) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).)
Western Blot (WB)
(KLF2 Antibody (N-term) (MBS9205028) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).)
Western Blot (WB)
(KLF2 Antibody (N-term)(MBS9205028) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).)
Western Blot (WB)
(KLF2 Antibody (N-term)(MBS9205028) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).)
Zahlten, J., et al. J. Immunol. 185(1):597-604(2010)
Wang, W., et al. Blood 115(14):2971-2979(2010)
Boon, R.A., et al. Blood 115(12):2533-2542(2010)
Villarreal, G. Jr., et al. Biochem. Biophys. Res. Commun. 391(1):984-989(2010)
NCBI and Uniprot Product Information
NCBI Description
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]
Uniprot Description
KLF2: Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein type: C2H2-type zinc finger protein; DNA-binding
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component: nucleus
Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity
Biological Process: erythrocyte maturation; transcription, DNA-dependent; in utero embryonic development; multicellular organism growth; negative regulation of interleukin-6 production; cell morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic; positive regulation of protein metabolic process
Research Articles on KLF2
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Product Notes
The KLF2 klf2 (Catalog #AAA9205028) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 13-42. The KLF2 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KLF2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA. WB~~1:1000. Researchers should empirically determine the suitability of the KLF2 klf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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