Rabbit KK-LC-1 Polyclonal Antibody | anti-KK-LC-1 antibody
KK-LC-1 Antibody
Immunoprecipitation: 1:200
Western Blot: 1:500
A lung adenocarcinoma tumor specific CTL clone H1 obtained from the lymph node lymphocytes of patient was used to identify a new antigen coding gene by cDNA expression cloning technique. The gene consist of 556 bp including an open reading frame consist of 113 amino acids name as KiTA-kyushu lung cancer antigen 1(KK-LC1)the epitope for this protein lies between aa 76-84 and the genomic DNA of this antigen was localized on chromosome Xq22. The RT analyses suggests that the mRNA for this gene is only expressed in the testis among all the normal tissues. About 50% of the non-small-cell lung carcinoma and 40% of the non-small cell lung cancer tissue are positive for the expression of this protein.
The KKLC-1 selective antibodies were generated against unique peptide taken form within the coding region of the KKLCA1 gene. MBS has generated highly specific rabbit anti-KKLCA1 polyclonal antibodies utilizing small peptide sequences . MBS has produced antibodies to multiple epitopes on the same protein that will facilitate studies utilizing interspecies cross reactivity (mbs541954, MBS541955, MBS541956). The antibodies to to kklca1 can be conjugated to fluorophores ant other secondary enzymes as an additional service.
NCBI and Uniprot Product Information
Uniprot Description
KKLC1:
Protein type: Cancer Testis Antigen (CTA); Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq23
Cellular Component: integral to membrane; nucleus; plasma membrane
Research Articles on KK-LC-1
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Product Notes
The KK-LC-1 ct83 (Catalog #AAA541956) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KK-LC-1 Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's KK-LC-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the KK-LC-1 ct83 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KK-LC-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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