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Testing Data

Rabbit anti-Rat Kir6.1 Polyclonal Antibody | anti-Kir6.1 antibody

Anti-Kir6.1 Antibody

Gene Names
KCNJ8; Kir6.1
Reactivity
Rat
Applications
Western Blot
Purity
Affinity Purified On Immobilized Antigen.
Synonyms
Kir6.1; Polyclonal Antibody; Anti-Kir6.1 Antibody; anti-Kir6.1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody is specific for Kir6.1, it does not cross react with Kir6.2.
Purity/Purification
Affinity Purified On Immobilized Antigen.
Form/Format
Liquid; PBS, pH 7.4 with 0.05% sodium azide.
Concentration
1ug/ul (varies by lot)
Sequence Length
287
Applicable Applications for anti-Kir6.1 antibody
Western Blot (WB)
Application Notes
WB: Rat heart membranes (1:200)
Immunogen
Peptide (C)KRNSMRRNNSMRRSN, corresponding to amino acid residues 382-396 of rat Kir6.1 (Accession number Q63664).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Testing Data

Testing Data

Testing Data
Related Product Information for anti-Kir6.1 antibody
ATP-sensitive inward rectifier K+ channel Kir6.1, KCNJ8 Kir 6.1 is a member of the inward rectifier K+ channels (Kir channels), a large family of voltage-independent K+ channels largely involved in stabilization of the membrane resting potential and in K+ transport across membranes. Kir 6.1 like its close relative Kir 6.2 is highly sensitive to inhibition by intracellular ATP. Closure of the channel leads to membrane depolarization hence coupling intracellular metabolism to cellular excitability. Kir 6.1 presents the common topology of the inward-rectifier superfamily: two transmembrane domains flanking a highly conserved pore region with the N and C-terminus located intracellularly. The functional ATP sensitive channel (KATP) is composed of octamers of four Kir 6.x subunits and four members of the sulfonylurea receptor family SUR1, SUR2A and SUR2B. Kir 6.1 tissue distribution is relatively broad with expression detected in heart, brain, and smooth muscle.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
Kir6.1, partial
NCBI Official Symbol
KCNJ8
NCBI Official Synonym Symbols
Kir6.1
NCBI Protein Information
ATP-sensitive inward rectifier potassium channel 8

Research Articles on Kir6.1

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Product Notes

The Kir6.1 (Catalog #AAA4159239) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kir6.1 Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Kir6.1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: Rat heart membranes (1:200). Researchers should empirically determine the suitability of the Kir6.1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kir6.1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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