Rabbit anti-Human, Mouse KIF21B Polyclonal Antibody | anti-KIF21B antibody
KIF21B Antibody
Gene Names
KIF21B; FLJ16314
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
KIF21B; Polyclonal Antibody; KIF21B Antibody; KI21B_HUMAN; KIAA0449; Kinesin-like protein KIF21B; anti-KIF21B antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
KIF21B Antibody detects endogenous levels of total KIF21B.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-KIF21B antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Subunit Structure
Interacts with TRIM3; the interaction positively affects motility of KIF21B. Interacts with GABARAP and GABA(A) receptor subunits: GABRG2, GABRA1 and GABRA2. May interact with GABA(A) receptor subunits: GABRB2 and GABRB3.
Function
Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-KIF21B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
182,662 Da
NCBI Official Full Name
kinesin-like protein KIF21B
NCBI Official Synonym Full Names
kinesin family member 21B
NCBI Official Symbol
KIF21B
NCBI Official Synonym Symbols
FLJ16314
NCBI Protein Information
kinesin-like protein KIF21B; OTTHUMP00000033935; OTTHUMP00000228887; OTTHUMP00000228888; OTTHUMP00000228889
UniProt Protein Name
Kinesin-like protein KIF21B
Protein Family
UniProt Gene Name
KIF21B
UniProt Synonym Gene Names
KIAA0449
UniProt Entry Name
KI21B_HUMAN
NCBI Description
KIF21B belongs to a family of plus end-directed kinesin (see MIM 600025) motor proteins. Neurons use kinesin and dynein (see MIM 600112) microtubule-dependent motor proteins to transport essential cellular components along axonal and dendritic microtubules.[supplied by OMIM]
Uniprot Description
KIF21B: Microtubule-binding motor protein probably involved in neuronal dendritic transport. In vitro, has a plus-end directed motor activity. Belongs to the kinesin-like protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Microtubule-binding
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: microtubule; kinesin complex; cytoplasm
Molecular Function: microtubule binding; ATPase activity; microtubule motor activity; ATP binding
Biological Process: metabolic process; microtubule-based movement
Research Articles on KIF21B
1. Data show the association of SNPs in KIF21B with multiple sclerosis in a Belgian study population.
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Product Notes
The KIF21B kif21b (Catalog #AAA9629559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIF21B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KIF21B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the KIF21B kif21b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF21B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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