Western Blot (WB)
(Western blot analysis of extracts of Mouse brain? tissue sample,using KIF1B Antibody.)
Rabbit KIF1B Polyclonal Antibody | anti-KIF1B antibody
KIF1B Antibody
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog
ELISA (Peptide): 1:20000-1:40000
Western Blot (WB)
(Western blot analysis of extracts of Mouse brain? tissue sample,using KIF1B Antibody.)
Western Blot (WB)
(Western blot analysis of extracts of Mouse brain? tissue sample,using KIF1B Antibody.)
Subunit Structure: Interacts (via C-terminus end of the kinesin-motor domain) with CHP1; the interaction occurs in a calcium-dependent manner (By similarity). Interacts with KBP.
Similarity: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.
NCBI and Uniprot Product Information
Predicted: 205 kDa
NCBI Description
This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008]
Uniprot Description
KIF1B: a member of the kinesin motor protein family. Motor for anterograde transport of mitochondria. May play a role in synaptic vesicle transport. Has a microtubule plus end-directed motility. Aberrant expression seen in neuroblastoma. Mutated in Charcot-Marie-Tooth disease.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 1p36.2
Cellular Component: microtubule; kinesin complex; neuron projection; microtubule associated complex; cytoplasmic vesicle membrane; mitochondrion; cytoplasmic vesicle
Molecular Function: protein binding; kinesin binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding
Biological Process: vesicle-mediated transport; apoptosis; metabolic process; neuromuscular synaptic transmission; nerve-nerve synaptic transmission; cytoskeleton-dependent intracellular transport; anterograde axon cargo transport; microtubule-based movement; mitochondrion transport along microtubule
Disease: Charcot-marie-tooth Disease, Axonal, Type 2a1; Neuroblastoma, Susceptibility To; Pheochromocytoma
Research Articles on KIF1B
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Product Notes
The KIF1B kif1b (Catalog #AAA9610917) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIF1B Antibody reacts with Human, Mouse Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's KIF1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Peptide ELISA (EIA). WB: 1:500-1:2000 ELISA (Peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the KIF1B kif1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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