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Guinea Pig Keratin K6 Polyclonal Antibody | anti-Krt16 antibody

Keratin K6 antibody

Gene Names
Krt16; K16; Krt1-16; AI324768
Applications
Immunofluorescence, Immunohistochemistry
Synonyms
Keratin K6; Polyclonal Antibody; Keratin K6 antibody; Polyclonal Keratin K6; Anti Keratin K6; Keratin K 6; Keratin K-6; Cytokeratin 6; anti-Krt16 antibody
Ordering
For Research Use Only!
Host
Guinea Pig
Clonality
Polyclonal
Specificity
Human Keratin K6
Form/Format
Supplied in liquid form. Contains 0.09% sodium azide
Sequence Length
469
Applicable Applications for anti-Krt16 antibody
Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes
IHC: 1:100-1:200
Biological Significance
Keratins are the intermediate filament proteins that form a dense meshwork of filaments throughout the cytoplasm of epithelial cells. Keratins form heteropolymers consisting of a type I and a type II keratin. Keratins are generally expressed in particular pairs of type I and type II keratin proteins in a tissue-specific and cellular differentiation-specific manner.
Cross-Reactivity
Mouse
Immunogen
Keratin K6 antibody was raised in Guinea Pig using synthetic peptide of human keratin K6 coupled to KLH as the immunogen.
Preparation and Storage
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-Krt16 antibody
Guinea Pig polyclonal Keratin K6 antibody
Product Categories/Family for anti-Krt16 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,606 Da
NCBI Official Full Name
keratin, type I cytoskeletal 16
NCBI Official Synonym Full Names
keratin 16
NCBI Official Symbol
Krt16
NCBI Official Synonym Symbols
K16; Krt1-16; AI324768
NCBI Protein Information
keratin, type I cytoskeletal 16
UniProt Protein Name
Keratin, type I cytoskeletal 16
Protein Family
UniProt Gene Name
Krt16
UniProt Synonym Gene Names
Krt1-16; CK-16; K16
UniProt Entry Name
K1C16_MOUSE

Uniprot Description

K16: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K6. K16 and K17 are coexpressed only in pathological situations such as metaplasias and carcinomas of the uterine cervix and in psoriasis vulgaris.

Protein type: Cytoskeletal

Cellular Component: cytoskeleton; intermediate filament; nucleus

Molecular Function: protein binding; structural constituent of cytoskeleton; structural molecule activity

Biological Process: keratinocyte differentiation; immune system process; keratinization; intermediate filament cytoskeleton organization and biogenesis; innate immune response; morphogenesis of an epithelium; inflammatory response; negative regulation of cell migration; keratinocyte migration; aging; hair cycle

Research Articles on Krt16

Similar Products

Product Notes

The Krt16 krt16 (Catalog #AAA833793) is an Antibody produced from Guinea Pig and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Keratin K6 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC). IHC: 1:100-1:200. Researchers should empirically determine the suitability of the Krt16 krt16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Keratin K6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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