Western Blot (WB)
(Host: RabbitTarget Name: KELSample Type: 721_B Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Rabbit anti-Human KEL Polyclonal Antibody | anti-KEL antibody
KEL Antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: KELSample Type: 721_B Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: KELSample Type: 721_B Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Target Description: This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]
Uniprot Description
KEL: Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. Belongs to the peptidase M13 family.
Protein type: Membrane protein, integral; Protease; EC 3.4.24.-
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: plasma membrane; integral to membrane
Molecular Function: protein binding; metalloendopeptidase activity; metal ion binding
Biological Process: cellular calcium ion homeostasis; myelination; vasoconstriction; regulation of axon diameter; skeletal muscle fiber development; proteolysis; regulation of cell size
Disease: Blood Group--kell System
Research Articles on KEL
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Product Notes
The KEL kel (Catalog #AAA3215947) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KEL Antibody - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KEL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the KEL kel for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PCETSVCLDL RDHYLASGNT SVAPCTDFFS FACGRAKETN NSFQELATKN. It is sometimes possible for the material contained within the vial of "KEL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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