Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7600749 (KEAP1 antibody) at dilution of 1:100)
Rabbit KEAP1 Polyclonal Antibody | anti-KEAP1 antibody
KEAP1 Rabbit Polyclonal
Gene Names
Keap1; CG3962; dkeap-1; dkeap1; dKeap1; dKEAP1; DmelCG3962; keap1; KEAP1; Nrf-2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
>=95% as determined by SDS-PAGEImmunogen Affinity Purified
Synonyms
KEAP1; Polyclonal Antibody; KEAP1 Rabbit Polyclonal; Cytosolic inhibitor of Nrf2; INrf2; Kelch like protein 19; KIAA0132; KLHL19; anti-KEAP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, Mouse ,Rat; other species are not tested. Please decide the specificity by homology
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
776
Applicable Applications for anti-KEAP1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
WB : 1:1000-1:10000
IP : 1:200-1:2000
IHC : 1:50-1:200
IP : 1:200-1:2000
IHC : 1:50-1:200
Immunogen
Kelch-like ECH-associated protein 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7600749 (KEAP1 antibody) at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7600749 (KEAP1 antibody) at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescence analysis of A549 cells using MBS7600749 (KEAP1 antibody) .)
Immunofluorescence (IF)
(Immunofluorescence analysis of A549 cells using MBS7600749 (KEAP1 antibody) .)
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7600749 (KEAP1 antibody) at dilution of 1:1000)
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7600749 (KEAP1 antibody) at dilution of 1:1000)
Related Product Information for anti-KEAP1 antibody
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55-70 kDa
NCBI Official Full Name
Keap1, isoform B
NCBI Official Symbol
Keap1
NCBI Official Synonym Symbols
CG3962; dkeap-1; dkeap1; dKeap1; dKEAP1; DmelCG3962; keap1; KEAP1; Nrf-2
NCBI Protein Information
CG3962 gene product from transcript CG3962-RC
Protein Family
Research Articles on KEAP1
Similar Products
Product Notes
The KEAP1 (Catalog #AAA7600749) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KEAP1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KEAP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). WB : 1:1000-1:10000 IP : 1:200-1:2000 IHC : 1:50-1:200. Researchers should empirically determine the suitability of the KEAP1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KEAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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