Rabbit KCNT1 Polyclonal Antibody | anti-KCNT1 antibody

KCNT1 Antibody

Cat. Num. AAA9506708

• Gene Names: KCNT1; ENFL5; SLACK; EIEE14; KCa4.1; Slo2.2; bA100C15.2
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, ELISA
• Purity: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Synonyms: KCNT1; Polyclonal Antibody; KCNT1 Antibody; anti-KCNT1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: KCNT1 Antibody detects endogenous levels of total KCNT1 protein.
• Purity/Purification: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 1,211

• Applicable Applications for anti-KCNT1 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50~1:100; ELISA: 1:10000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from human KCNT1.
• Immunogen Range: 1019-1068
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNT1 Antibody. The picture on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 432134244
• NCBI GeneID: 57582
• NCBI Accession #: NP_001258932.1
• NCBI GenBank Nucleotide #: NM_001272003.1
• UniProt Accession #: Q5JUK3; Q9P2C5; B3KXF7; B7ZVY4; B9EGP2; G5E9V0
• Molecular Weight: 138 kDa
• NCBI Official Full Name: potassium channel subfamily T member 1 isoform 2
• NCBI Official Synonym Full Names: potassium sodium-activated channel subfamily T member 1
• NCBI Official Symbol: KCNT1
• NCBI Official Synonym Symbols: ENFL5; SLACK; EIEE14; KCa4.1; Slo2.2; bA100C15.2
• NCBI Protein Information: potassium channel subfamily T member 1
• UniProt Protein Name: Potassium channel subfamily T member 1
• Protein Family: Potassium channel subfamily
• UniProt Gene Name: KCNT1
• UniProt Synonym Gene Names: KIAA1422

NCBI Description

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Uniprot Description

Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) ().