Rabbit anti-Human KCNK9 Polyclonal Antibody | anti-KCNK9 antibody

KCNK9 Antibody

Cat. Num. AAA9414837

• Gene Names: KCNK9; KT3.2; TASK3; K2p9.1; TASK-3
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: KCNK9; Polyclonal Antibody; KCNK9 Antibody; KT3.2; TASK3; K2p9.1; TASK-3; anti-KCNK9 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total KCNK9 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2.8 mg/ml (varies by lot)
• Sequence Length: 374

• Applicable Applications for anti-KCNK9 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:500-1:2000; Immunohistochemistry: 1:100-1:300
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human potassium channel, subfamily K, member 9
• Target Name: KCNK9
• Preparation and Storage: Store at -20 degree C

Testing Data

(Gel: 8%SDS-PAGE Lysates (from left to right): Human paraneoplastic and normal kidney tissue)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40.)

Related Product Information for anti-KCNK9 antibody

This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.

Product Categories/Family for anti-KCNK9 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 542133161
• NCBI GeneID: 51305
• NCBI Accession #: NP_001269463.1
• NCBI GenBank Nucleotide #: NM_001282534.1
• UniProt Accession #: Q9NPC2; Q2M290; Q540F2
• Molecular Weight: 42kd
• NCBI Official Full Name: potassium channel subfamily K member 9
• NCBI Official Synonym Full Names: potassium channel, two pore domain subfamily K, member 9
• NCBI Official Symbol: KCNK9
• NCBI Official Synonym Symbols: KT3.2; TASK3; K2p9.1; TASK-3
• NCBI Protein Information: potassium channel subfamily K member 9
• UniProt Protein Name: Potassium channel subfamily K member 9
• Protein Family: Potassium channel subfamily
• UniProt Gene Name: KCNK9
• UniProt Synonym Gene Names: TASK3; Two pore K(+) channel KT3.2
• UniProt Entry Name: KCNK9_HUMAN

NCBI Description

This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

KCNK9: pH-dependent, voltage-insensitive, background potassium channel protein. Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: synaptic vesicle; integral to membrane; plasma membrane

Molecular Function: protein homodimerization activity; potassium channel activity; protein heterodimerization activity; voltage-gated ion channel activity

Biological Process: synaptic transmission; potassium ion transport

Disease: Birk-barel Mental Retardation Dysmorphism Syndrome