Western Blot (WB)
(KCNK1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KCNK1 antibody detected the KCNK1 protein (arrow).)
Rabbit anti-Human KCNK1 Polyclonal Antibody | anti-KCNK1 antibody
KCNK1, CT (KCNK1, HOHO1, KCNO1, TWIK1, Potassium channel subfamily K member 1, Inward rectifying potassium channel protein TWIK-1, Potassium channel KCNO1) (PE)
Gene Names
KCNK1; DPK; HOHO; K2P1; KCNO1; TWIK1; K2p1.1; TWIK-1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
KCNK1; Polyclonal Antibody; CT (KCNK1; HOHO1; KCNO1; TWIK1; Potassium channel subfamily K member 1; Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1) (PE); Potassium channel KCNO1; anti-KCNK1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-KCNK1 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
KCNK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human KCNK1.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(KCNK1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KCNK1 antibody detected the KCNK1 protein (arrow).)
Western Blot (WB)
(KCNK1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KCNK1 antibody detected the KCNK1 protein (arrow).)
Related Product Information for anti-KCNK1 antibody
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
Product Categories/Family for anti-KCNK1 antibody
References
Feliciangeli, S., et al. J. Biol. Chem. 285(7):4798-4805(2010). McGeachie, M., et al. Circulation 120(24):2448-2454(2009). Zhou, M., et al. J. Neurosci. 29(26):8551-8564(2009). Goldstein, S.A., et al. Pharmacol. Rev. 57(4):527-540(2005). Rajan, S., et al. Cell 121(1):37-47(2005).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,143 Da
NCBI Official Full Name
potassium channel subfamily K member 1
NCBI Official Synonym Full Names
potassium channel, subfamily K, member 1
NCBI Official Symbol
KCNK1
NCBI Official Synonym Symbols
DPK; HOHO; K2P1; KCNO1; TWIK1; K2p1.1; TWIK-1
NCBI Protein Information
potassium channel subfamily K member 1; potassium channel KCNO1; inward rectifying potassium channel protein TWIK-1; potassium inwardly-rectifying channel, subfamily K, member 1
UniProt Protein Name
Potassium channel subfamily K member 1
Protein Family
UniProt Gene Name
KCNK1
UniProt Synonym Gene Names
HOHO1; KCNO1; TWIK1
UniProt Entry Name
KCNK1_HUMAN
NCBI Description
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]
Uniprot Description
KCNK1: Weakly inward rectifying potassium channel. Homodimer (Potential). Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1q42-q43
Cellular Component: voltage-gated potassium channel complex; brush border membrane; apical plasma membrane; plasma membrane; endosome
Molecular Function: inward rectifier potassium channel activity
Biological Process: response to nicotine; synaptic transmission; potassium ion transport
Research Articles on KCNK1
Similar Products
Product Notes
The KCNK1 kcnk1 (Catalog #AAA6312620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNK1, CT (KCNK1, HOHO1, KCNO1, TWIK1, Potassium channel subfamily K member 1, Inward rectifying potassium channel protein TWIK-1, Potassium channel KCNO1) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KCNK1 kcnk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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