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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using KCNK1 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.)

Rabbit KCNK1 Polyclonal Antibody | anti-KCNK1 antibody

KCNK1 Polyclonal Antibody

Gene Names
KCNK1; DPK; HOHO; K2P1; KCNO1; TWIK1; K2p1.1; TWIK-1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purification
Synonyms
KCNK1; Polyclonal Antibody; KCNK1 Polyclonal Antibody; DPK; HOHO; K2P1; K2p1.1; KCNO1; TWIK-1; TWIK1; anti-KCNK1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Sequence Length
336
Applicable Applications for anti-KCNK1 antibody
WB, IHC.
Application Notes
WB: 1:500 - 1:2000
IHC: 1:50-1:200
Immunogen
Recombinant protein containing a sequence corresponding to amino acids 267-336 of human KCNK1 (NP_002236.1)
Calculated MW
38 kDa
Observed MW
38 kDa
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20°C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using KCNK1 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using KCNK1 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat heart using KCNK1 antibody MBS9132644 at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat heart using KCNK1 antibody MBS9132644 at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC)

( Immunohistochemistry of paraffin-embedded mouse lung using KCNK1 antibody (MBS9132644)at dilution of 1:100 (40x lens))

Immunohistochemistry (IHC) ( Immunohistochemistry of paraffin-embedded mouse lung using KCNK1 antibody (MBS9132644)at dilution of 1:100 (40x lens))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse heart using KCNK1 antibody (MBS9132644) at dilution of 1:100 (40x lens))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse heart using KCNK1 antibody (MBS9132644) at dilution of 1:100 (40x lens))
Related Product Information for anti-KCNK1 antibody
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
Product Categories/Family for anti-KCNK1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Potassium channel subfamily K member 1
NCBI Official Synonym Full Names
potassium two pore domain channel subfamily K member 1
NCBI Official Symbol
KCNK1
NCBI Official Synonym Symbols
DPK; HOHO; K2P1; KCNO1; TWIK1; K2p1.1; TWIK-1
NCBI Protein Information
potassium channel subfamily K member 1
UniProt Protein Name
Potassium channel subfamily K member 1
UniProt Gene Name
KCNK1

NCBI Description

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNK1: Weakly inward rectifying potassium channel. Homodimer (Potential). Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q42.2

Cellular Component: integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; plasma membrane; voltage-gated potassium channel complex

Molecular Function: inward rectifier potassium channel activity; potassium channel activity; potassium ion leak channel activity; sodium channel activity; voltage-gated potassium channel activity

Biological Process: potassium ion transport; regulation of resting membrane potential

Research Articles on KCNK1

Similar Products

Product Notes

The KCNK1 kcnk1 (Catalog #AAA9132644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNK1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KCNK1 can be used in a range of immunoassay formats including, but not limited to, WB, IHC. WB: 1:500 - 1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the KCNK1 kcnk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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