Immunohistochemistry (IHC)
(Anti-KCNE3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)
Goat KCNE3 Polyclonal Antibody | anti-KCNE3 antibody
Goat Polyclonal to Human KCNE3
Predicted Reactivity: Monkey, Mouse (at least 90% immunogen sequence identity)
Predicted Reactivity: Monkey, Mouse (at least 90% immunogen sequence identity)
Usage: Peptide ELISA: antibody detection limit dilution 1:1000. Western blot: Preliminary experiments in Human, Mouse and Rat Skeletal Muscle lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml).
Immunohistochemistry (IHC)
(Anti-KCNE3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)
Immunohistochemistry (IHC)
(Anti-KCNE3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
Uniprot Description
KCNE3: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Belongs to the potassium channel KCNE family.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component: voltage-gated potassium channel complex
Molecular Function: voltage-gated potassium channel activity; potassium channel regulator activity
Disease: Brugada Syndrome 6
Research Articles on KCNE3
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Product Notes
The KCNE3 kcne3 (Catalog #AAA244650) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human KCNE3 reacts with Gibbon, Gorilla, Hamster, Human Predicted Reactivity: Monkey, Mouse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's KCNE3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA (1:1000), IHC-P (3.75 ug/ml) Usage: Peptide ELISA: antibody detection limit dilution 1:1000. Western blot: Preliminary experiments in Human, Mouse and Rat Skeletal Muscle lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml). Researchers should empirically determine the suitability of the KCNE3 kcne3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNE3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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