Western Blot (WB)
Rabbit JMJD3 Polyclonal Antibody | anti-JMJD3 antibody
JMJD3 Antibody
Gene Names
KDM4C; GASC1; JHDM3C; JMJD2C; TDRD14C
Reactivity
Human, Monkey
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Affinity Purified
Synonyms
JMJD3; Polyclonal Antibody; JMJD3 Antibody; Affinity Purified JmjC domain-containing histone demthylation protein 3C Antibody; Histone demethylase JMJD3 antibody; JmjC domain containing protein 3 antibody; Jumonji D3 antibody; Jumonji domain containing 3 antibody; Kdm6b antibody; KIAA0346 antibody; Lysine demethylase 6B antibody; anti-JMJD3 antibody
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Specificity
Cross reactive to isotypes of 3C only.
Purity/Purification
Affinity Purified
Concentration
0.50 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
813
Applicable Applications for anti-JMJD3 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
IP: 1:200
WB: 1:500
IP: 1:200
WB: 1:500
Immunogen
Synthetic peptide taken within amino acid region 500-550 on JmjC domain-containing histone demthylation protein 3C.
Conjugation
Unconjugated
Molecular Function
Chromatin regulator; Dioxygenase; Oxidoreductase
Preparation and Storage
Store at -20 degree C for long term storage.
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-JMJD3 antibody
Overview: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Structure: Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Expression: Nucleus
Structure: Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Expression: Nucleus
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
94,376 Da
NCBI Official Full Name
lysine-specific demethylase 4C isoform 3
NCBI Official Synonym Full Names
lysine demethylase 4C
NCBI Official Symbol
KDM4C
NCBI Official Synonym Symbols
GASC1; JHDM3C; JMJD2C; TDRD14C
NCBI Protein Information
lysine-specific demethylase 4C
UniProt Protein Name
Lysine-specific demethylase 4C
UniProt Gene Name
KDM4C
UniProt Synonym Gene Names
GASC1; JHDM3C; JMJD2C; KIAA0780; GASC-1 protein
NCBI Description
This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Uniprot Description
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Research Articles on JMJD3
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Product Notes
The JMJD3 kdm4c (Catalog #AAA5400459) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JMJD3 Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's JMJD3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 IP: 1:200 WB: 1:500. Researchers should empirically determine the suitability of the JMJD3 kdm4c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JMJD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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