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Western Blot (WB) (Western Blot analysis of fetal testis and fetal kidney lysate with anti-IZUOMI antibody)

Rabbit IZUMO1 Polyclonal Antibody | anti-IZUMO1 antibody

IZUMO1 Antibody

Gene Names
IZUMO1; OBF; IZUMO
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
IZUMO1; Polyclonal Antibody; IZUMO1 Antibody; Rabbit Polyclonal IZUMO1 Antibody; Polyclonal IZUMO1 antibody; Anti-IZUMO1 antibody; 1700058F15Rik antibody; IZUM1 antibody; Izumo antibody; izumo sperm-egg fusion 1 antibody; Izumo sperm-egg fusion protein 1 antibody; Izumo1 antibody; OBF antibody; Oocyte binding/fusion factor antibody; Sperm-specific protein izumo antibody; anti-IZUMO1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in sterile H2O containing 1% BSA and 0.02% NaN3
Concentration
1 mg/ml (varies by lot)
Sequence Length
350
Applicable Applications for anti-IZUMO1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:1000-1:2000
IHC: 1:100-1:500
Immunogen
IZUMO1 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human IZUMO1 as the immunogen.
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of fetal testis and fetal kidney lysate with anti-IZUOMI antibody)

Western Blot (WB) (Western Blot analysis of fetal testis and fetal kidney lysate with anti-IZUOMI antibody)

Immunohistochemistry (IHC)

(Immunohistochemical staining of formalin-fixed paraffin-embedded fetal testis showing membrane staining with anti-IZUMOI antibody at a dilution of 1/100)

Immunohistochemistry (IHC) (Immunohistochemical staining of formalin-fixed paraffin-embedded fetal testis showing membrane staining with anti-IZUMOI antibody at a dilution of 1/100)
Related Product Information for anti-IZUMO1 antibody
IZUMO1 is involved in the fertilization process. May be involved in the fusion of the sperm with the egg.
Product Categories/Family for anti-IZUMO1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
izumo sperm-egg fusion protein 1 isoform 1
NCBI Official Synonym Full Names
izumo sperm-egg fusion 1
NCBI Official Symbol
IZUMO1
NCBI Official Synonym Symbols
OBF; IZUMO
NCBI Protein Information
izumo sperm-egg fusion protein 1
UniProt Protein Name
Izumo sperm-egg fusion protein 1
UniProt Gene Name
IZUMO1
UniProt Synonym Gene Names
OBF
UniProt Entry Name
IZUM1_HUMAN

NCBI Description

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]

Uniprot Description

IZUMO1: Involved in the fertilization process. May be involved in the fusion of the sperm with the egg. Belongs to the Izumo family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: acrosomal membrane; integral to membrane; plasma membrane

Molecular Function: protein homodimerization activity; receptor binding

Biological Process: cell adhesion; fusion of sperm to egg plasma membrane; single fertilization; sperm-egg recognition

Research Articles on IZUMO1

Similar Products

Product Notes

The IZUMO1 izumo1 (Catalog #AAA5313429) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IZUMO1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:1000-1:2000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the IZUMO1 izumo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IZUMO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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