Immunohistochemistry (IHC)
(Human Stomach)
Rabbit IVNS1ABP Polyclonal Antibody | anti-IVNS1ABP antibody
IVNS1ABP antibody - N-terminal region
Immunohistochemistry (IHC)
(Human Stomach)
Immunohistochemistry (IHC)
(Human Stomach)
Western Blot (WB)
(WB Suggested Anti-IVNS1ABP Antibody Titration: 2.0ug/mlPositive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-IVNS1ABP Antibody Titration: 2.0ug/mlPositive Control: HepG2 cell lysate)
Target Description: IVNS1ABP is a novel human protein that interacts with the influenza A virus. Nonstructural NS1 protein is relocalized in the nuclei of infected cells.
NCBI and Uniprot Product Information
Uniprot Description
IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Chromosomal Location of Human Ortholog: 1q25.1-q31.1
Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton
Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing
Research Articles on IVNS1ABP
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Product Notes
The IVNS1ABP ivns1abp (Catalog #AAA3201325) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IVNS1ABP antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's IVNS1ABP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the IVNS1ABP ivns1abp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL. It is sometimes possible for the material contained within the vial of "IVNS1ABP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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