Western Blot (WB)
(ITIH5 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ITIH5 antibody detected the ITIH5 protein (arrow).)
Rabbit anti-Human ITIH5 Polyclonal Antibody | anti-ITIH5 antibody
ITIH5, CT (ITIH5, KIAA1953, Inter-alpha-trypsin inhibitor heavy chain H5)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Western Blot (WB)
(ITIH5 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ITIH5 antibody detected the ITIH5 protein (arrow).)
Western Blot (WB)
(ITIH5 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ITIH5 antibody detected the ITIH5 protein (arrow).)
Immunohistochemistry (IHC)
(ITIH5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ITIH5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ITIH5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ITIH5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Uniprot Description
Function: May act as a tumor suppressor.
Subcellular location: Secreted
By similarity.
Tissue specificity: Abundantly expressed in placenta. Less abundant expression in mammary gland and ovary. Expression is barely detectable levels in all other tissues tested. Ref.1
Induction: Down-regulated in breast tumors. Ref.1
Sequence similarities: Belongs to the ITIH family.Contains 1 VIT domain.Contains 1 VWFA domain.
Caution: Conflict in position 933 in the human genome assembly due to a frameshift.
Sequence caution: The sequence CAI12953.1 differs from that shown. Reason: Frameshift at position 933. The sequence CAI12955.1 differs from that shown. Reason: Frameshift at position 933. The sequence CAI16360.1 differs from that shown. Reason: Frameshift at position 933. The sequence CAI16363.1 differs from that shown. Reason: Frameshift at position 933.
Research Articles on ITIH5
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Product Notes
The ITIH5 itih5 (Catalog #AAA649115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITIH5, CT (ITIH5, KIAA1953, Inter-alpha-trypsin inhibitor heavy chain H5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITIH5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the ITIH5 itih5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITIH5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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