Rabbit ITI-H3  Polyclonal Antibody | anti-ITI-H3  antibody

ITI-H3 (D651) polyclonal antibody

Cat. Num. AAA3014018

• Gene Names: ITIH3; H3P; SHAP; ITI-HC3
• Reactivity: Human, Rat, Mouse
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: ITI-H3 ; Polyclonal Antibody; ITI-H3 (D651) polyclonal antibody; Inter-alpha-trypsin inhibitor heavy chain H3; ITI heavy chain H3; ITI-HC3; Inter-alpha-inhibitor heavy chain 3; Serum-derived hyaluronan-associated protein; SHAP; ITIH3; anti-ITI-H3 antibody

• Host: Rabbit
• Reactivity: Human, Rat, Mouse
• Clonality: Polyclonal
• Specificity: ITI-H3 (D651) polyclonal antibody detects endogenous levels of ITI-H3 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
• Sequence Length: 890

• Applicable Applications for anti-ITI-H3 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 35-91 of Human ITI-H3.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of ITI-H3  (D651)  polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate (40ug) Lane2:H1792 whole cell lysate (40ug) Lane3:H9C2 whole cell lysate (40ug) Lane4:AML-12 whole cell lysate (40ug))

Related Product Information for anti-ITI-H3  antibody

Inter-alpha-trypsin inhibitor heavy chain H3, may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.

NCBI and Uniprot Product Information

• NCBI GI #: 133925809
• NCBI GeneID: 3699
• NCBI Accession #: NP_002208.3
• NCBI GenBank Nucleotide #: NP_002208.3
• UniProt Accession #: Q06033
• Molecular Weight: ~ 75kDa
• NCBI Official Full Name: inter-alpha-trypsin inhibitor heavy chain H3 preproprotein
• NCBI Official Synonym Full Names: inter-alpha-trypsin inhibitor heavy chain 3
• NCBI Official Symbol: ITIH3
• NCBI Official Synonym Symbols: H3P; SHAP; ITI-HC3
• NCBI Protein Information: inter-alpha-trypsin inhibitor heavy chain H3
• UniProt Protein Name: Inter-alpha-trypsin inhibitor heavy chain H3
• UniProt Gene Name: ITIH3
• UniProt Synonym Gene Names: ITI heavy chain H3; ITI-HC3; Inter-alpha-inhibitor heavy chain 3; SHAP

NCBI Description

This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. Polymorphisms of this gene may be associated with increased risk for schizophrenia and major depressive disorder. This gene is present in an inter-alpha-trypsin inhibitor family gene cluster on chromosome 3. [provided by RefSeq, Jul 2015]

Uniprot Description

May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.