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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125829(ITGAE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit anti-Human ITGAE Polyclonal Antibody | anti-ITGAE antibody

ITGAE Antibody

Gene Names
ITGAE; CD103; HUMINAE
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
ITGAE; Polyclonal Antibody; ITGAE Antibody; Integrin; alpha E (antigen CD103; human mucosal lymphocyte antigen 1; alpha polypeptide); anti-ITGAE antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-ITGAE antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:2000
WB: 1:200-1:1000
IHC: 1:50-1:200
Immunogen
Fusion protein of human ITGAE
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125829(ITGAE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125829(ITGAE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MBS7125829(ITGAE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MBS7125829(ITGAE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200))

SDS-Page

(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: LoVo cells, Primary antibody: MBS7125829(ITGAE Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)

SDS-Page (Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: LoVo cells, Primary antibody: MBS7125829(ITGAE Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)
Product Categories/Family for anti-ITGAE antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
130,159 Da
NCBI Official Full Name
Integrin alpha-E
NCBI Official Synonym Full Names
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
NCBI Official Symbol
ITGAE
NCBI Official Synonym Symbols
CD103; HUMINAE
NCBI Protein Information
integrin alpha-E; HML-1 antigen; integrin alpha-IEL; mucosal lymphocyte 1 antigen; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide
UniProt Protein Name
Integrin alpha-E
Protein Family
UniProt Gene Name
ITGAE
UniProt Entry Name
ITAE_HUMAN

NCBI Description

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]

Uniprot Description

ITGAE: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Belongs to the integrin alpha chain family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: plasma membrane; integrin complex; external side of plasma membrane

Molecular Function: metal ion binding

Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; cell adhesion

Research Articles on ITGAE

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Product Notes

The ITGAE itgae (Catalog #AAA7125829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITGAE Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITGAE can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:2000 WB: 1:200-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ITGAE itgae for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGAE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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