Rabbit anti-Human, Rat IRX3 Polyclonal Antibody | anti-IRX3 antibody

IRX3 Antibody

Cat. Num. AAA7105669

• Gene Names: IRX3; IRX-1; IRXB1
• Reactivity: Human, Rat
• Applications: ELISA, Western Blot
• Purity: >95%, Protein G purified
• Synonyms: IRX3; Polyclonal Antibody; IRX3 Antibody; Iroquois-class homeodomain protein IRX-3; Homeodomain protein IRXB1; Iroquois homeobox protein 3; IRXB1; anti-IRX3 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 501

• Applicable Applications for anti-IRX3 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:5000
• Immunogen: Recombinant Human Iroquois-class homeodomain protein IRX-3 protein (285-378AA)
• Conjugation: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: A549 whole cell lysate, Rat lung tissueAll lanes: IRX3 antibody at 5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 53 KDaObserved band size: 53 KDa)

Related Product Information for anti-IRX3 antibody

Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

Product Categories/Family for anti-IRX3 antibody

Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 226371735
• NCBI GeneID: 79191
• NCBI Accession #: NP_077312.2
• NCBI GenBank Nucleotide #: NM_024336.2
• UniProt Accession #: P78415; Q7Z4A4; Q7Z4A5; Q8IVC6
• Molecular Weight: 52,119 Da
• NCBI Official Full Name: iroquois-class homeodomain protein IRX-3
• NCBI Official Synonym Full Names: iroquois homeobox 3
• NCBI Official Symbol: IRX3
• NCBI Official Synonym Symbols: IRX-1; IRXB1
• NCBI Protein Information: iroquois-class homeodomain protein IRX-3
• UniProt Protein Name: Iroquois-class homeodomain protein IRX-3
• Protein Family: Iroquois-class homeodomain protein
• UniProt Gene Name: IRX3
• UniProt Synonym Gene Names: IRXB1

NCBI Description

IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009]

Uniprot Description

Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells ().