Western Blot (WB)
(The anti-ERN2 Pab is used in Western blot to detect ERN2 in mouse liver tissue lysate)
Rabbit anti-Human IRE2 Polyclonal Antibody
IRE2, CT (Serine/Threonine-protein kinase/Endoribonuclease IRE2, Inositol-requiring 2, hIRE2p, IRE1b, Ire1-beta, Endoplasmic Reticulum-to-nucleus Signaling 2, Serine/Threonine-protein Kinase, Endoribonuclease, ERN2)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
IRE2; Polyclonal Antibody; CT (Serine/Threonine-protein kinase/Endoribonuclease IRE2; Inositol-requiring 2; hIRE2p; IRE1b; Ire1-beta; Endoplasmic Reticulum-to-nucleus Signaling 2; Serine/Threonine-protein Kinase; Endoribonuclease; ERN2); Anti -IRE2; anti-IRE2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ERN2.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Applicable Applications for anti-IRE2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunogen
Synthetic peptide selected from the C-terminal region of human ERN2 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(The anti-ERN2 Pab is used in Western blot to detect ERN2 in mouse liver tissue lysate)
Western Blot (WB)
(The anti-ERN2 Pab is used in Western blot to detect ERN2 in mouse liver tissue lysate)
Related Product Information for anti-IRE2 antibody
ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Product Categories/Family for anti-IRE2 antibody
Similar Products
Product Notes
The IRE2 (Catalog #AAA627356) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IRE2, CT (Serine/Threonine-protein kinase/Endoribonuclease IRE2, Inositol-requiring 2, hIRE2p, IRE1b, Ire1-beta, Endoplasmic Reticulum-to-nucleus Signaling 2, Serine/Threonine-protein Kinase, Endoribonuclease, ERN2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IRE2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the IRE2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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