Rabbit anti-Human IP6K3 Polyclonal Antibody | anti-IP6K3 antibody

IP6K3, NT (IP6K3, IHPK3, Inositol hexakisphosphate kinase 3, Inositol hexaphosphate kinase 3) (PE)

Cat. Num. AAA6310706

• Gene Names: IP6K3; IHPK3; INSP6K3
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: IP6K3; Polyclonal Antibody; NT (IP6K3; IHPK3; Inositol hexakisphosphate kinase 3; Inositol hexaphosphate kinase 3) (PE); Inositol hexaphosphate kinase 3; anti-IP6K3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-IP6K3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: IP6K3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the N-terminal region of human IP6K3.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(IP6K3 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IP6K3 antibody detected the IP6K3 protein (arrow).)

Related Product Information for anti-IP6K3 antibody

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.

Product Categories/Family for anti-IP6K3 antibody

Antibodies; Protein Kinases

References

Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010). Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009): Saiardi, A., et al. J. Biol. Chem. 276(42):39179-39185(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 218777830
• NCBI GeneID: 117283
• NCBI Accession #: NP_001136355.1
• NCBI GenBank Nucleotide #: NM_001142883.1
• UniProt Accession #: Q96PC2; Q96MQ9
• Molecular Weight: 46,417 Da
• NCBI Official Full Name: inositol hexakisphosphate kinase 3
• NCBI Official Synonym Full Names: inositol hexakisphosphate kinase 3
• NCBI Official Symbol: IP6K3
• NCBI Official Synonym Symbols: IHPK3; INSP6K3
• NCBI Protein Information: inositol hexakisphosphate kinase 3; InsP6 kinase 3; inositol hexaphosphate kinase 3; ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
• UniProt Protein Name: Inositol hexakisphosphate kinase 3
• Protein Family: Inositol hexakisphosphate kinase
• UniProt Gene Name: IP6K3
• UniProt Synonym Gene Names: IHPK3; InsP6 kinase 3
• UniProt Entry Name: IP6K3_HUMAN

NCBI Description

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]

Uniprot Description

IHPK3: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Belongs to the inositol phosphokinase (IPK) family.

Protein type: Kinase, other; Motility/polarity/chemotaxis; EC 2.7.4.21

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: cytoplasm; nucleus; cytosol

Molecular Function: inositol hexakisphosphate 6-kinase activity; inositol hexakisphosphate 5-kinase activity; inositol trisphosphate 3-kinase activity; ATP binding

Biological Process: inositol phosphate metabolic process; phosphatidylinositol metabolic process; protein amino acid phosphorylation; inositol phosphate biosynthetic process