Western Blot (WB)
(Western Blot (WB) analysis of INTS4 polyclonal antibody)
Rabbit INTS4 Polyclonal Antibody | anti-INTS4 antibody
INTS4 Polyclonal Antibody
Gene Names
INTS4; INT4; MST093
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
INTS4; Polyclonal Antibody; INTS4 Polyclonal Antibody; Integrator complex subunit 4; Int4; MSTP093; anti-INTS4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
INTS4 polyclonal antibody detects endogenous levels of INTS4 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
963
Applicable Applications for anti-INTS4 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant full length Human INTS4.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of INTS4 polyclonal antibody)
Western Blot (WB)
(Western Blot (WB) analysis of INTS4 polyclonal antibody)
Related Product Information for anti-INTS4 antibody
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3-end processing. INTS4 (Integrator complex subunit 4) is a 963 amino acid protein that contains eight HEAT repeats and is a component of the integrator complex. Localized to the nucleus, INTS4 plays a role in the processing of select snRNAs and mediates snRNA transcriptional regulation events. Four isoforms of INTS4 are expressed due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 108kDa
NCBI Official Full Name
integrator complex subunit 4
NCBI Official Synonym Full Names
integrator complex subunit 4
NCBI Official Symbol
INTS4
NCBI Official Synonym Symbols
INT4; MST093
NCBI Protein Information
integrator complex subunit 4
UniProt Protein Name
Integrator complex subunit 4
Protein Family
UniProt Gene Name
INTS4
UniProt Synonym Gene Names
Int4
UniProt Entry Name
INT4_HUMAN
NCBI Description
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Research Articles on INTS4
Similar Products
Product Notes
The INTS4 ints4 (Catalog #AAA3011517) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INTS4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's INTS4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the INTS4 ints4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INTS4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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