Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Interleukin 3 Receptor Alpha (IL3Ra) Polyclonal Antibody | anti-IL3Ra antibody
Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra)
MGHHHHHHSGSEF-TK EGKPWAGAEN LTCWIHDVDF LSCSWAVGPG APADVQYDLY LNVANRRQQY ECLHYKTDAQ GTRIGCRFDD ISRLSSGSQS SHILVRGRSA AFGIPCTDKF VVFSQIEILT PPNMTAKCNK THSFMHWKMR SHFNRKF
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded kidney tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded kidney tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
Uniprot Description
IL3RA: This is a receptor for interleukin-3. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.2
Cellular Component: integral component of membrane; intracellular; plasma membrane
Molecular Function: interleukin-3 receptor activity; protein tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity
Biological Process: MAPK cascade; peptidyl-tyrosine phosphorylation; positive regulation of GTPase activity
Research Articles on IL3Ra
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Product Notes
The IL3Ra il3ra (Catalog #AAA2001865) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Interleukin 3 Receptor Alpha (IL3Ra) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the IL3Ra il3ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-TK EGKPWAGAEN LTCWIHDVDF LSCSWAVGPG APADVQYDLY LNVANRRQQY ECLHYKTDAQ GTRIGCRFDD ISRLSSGSQS SHILVRGRSA AFGIPCTDKF VVFSQIEILT PPNMTAKCNK THSFMHWKMR SHFNRKF. It is sometimes possible for the material contained within the vial of "Interleukin 3 Receptor Alpha (IL3Ra), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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