Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7600577 (ITGA3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L))
Rabbit anti-Human Integrin alpha-3 Polyclonal Antibody | anti-ITGA3 antibody
Integrin alpha-3 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7600577 (ITGA3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7600577 (ITGA3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L))
Immunoprecipitation (IP)
(IP Result of anti-ITGA3 (IP: MBS7600577, 4ug; Detection: MBS7600577 1:500) with PC-3 cells lysate 2000ug.)
Immunoprecipitation (IP)
(IP Result of anti-ITGA3 (IP: MBS7600577, 4ug; Detection: MBS7600577 1:500) with PC-3 cells lysate 2000ug.)
Western Blot (WB)
(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS7600577 (ITGA3 antibody) at dilution of 1:500)
Western Blot (WB)
(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS7600577 (ITGA3 antibody) at dilution of 1:500)
NCBI and Uniprot Product Information
NCBI Description
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
Uniprot Description
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Research Articles on ITGA3
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Product Notes
The ITGA3 itga3 (Catalog #AAA7600577) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Integrin alpha-3 Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin alpha-3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ITGA3 itga3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin alpha-3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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