Sheep anti-Human Insulin-Like Growth Factor Binding Protein-Related Protein 10 Polyclonal Antibody | anti-IGFBPL1 antibody
Insulin-Like Growth Factor Binding Protein-Related Protein 10 (IGFBP-rP10, Kazal-type Serine Protease Inhibitor Domain-containing Protein 1, Bone and Odontoblast-expressed Protein 1, Insulin-like Growth Factor-binding-related Protein 10, IGFBP-rP10, IGFBP
Gene Names
IGFBPL1; IGFBPRP4; IGFBP-RP4; bA113O24.1
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Insulin-Like Growth Factor Binding Protein-Related Protein 10; Polyclonal Antibody; Insulin-Like Growth Factor Binding Protein-Related Protein 10 (IGFBP-rP10; Kazal-type Serine Protease Inhibitor Domain-containing Protein 1; Bone and Odontoblast-expressed Protein 1; Insulin-like Growth Factor-binding-related Protein 10; IGFBP-rP10; IGFBP; Anti -Insulin-Like Growth Factor Binding Protein-Related Protein 10 (IGFBP-rP10; anti-IGFBPL1 antibody
Host
Sheep
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human IGFBP-rP10. Species sequence homology: mouse (87%)
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 50ug/1ug BSA. Labeled with Biotin. Reconstitute with sterile TBS, pH 7.3, 20mM Trizma, 150mM sodium chloride, 0.1% BSA.
Applicable Applications for anti-IGFBPL1 antibody
Western Blot (WB)
Application Notes
Western Blot: 0.1-0.2ug/ml, Optimal dilutions to be determined by the researcher.
Immunogen
Purified, NS0-derived, recombinant human IGFBP-rP10 (aa31-304; Accession # Q96I82).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-IGFBPL1 antibody
IGFBP-rP10 (IGF binding protein-related protein 10; also Kazal-type serine protease inhibitor domain-contain protein 1 and BONO1) is a 37kD (predicted), secreted member of the IGFBP superfamily. It is expressed by osteoblasts and odontoblasts, is associated with regions of mineralization, and stimulates the proliferation of osteoblasts in vitro. Mature human IGFBP-rP10 is 274 aa in length. It contains an IGF binding domain (aa49-124), a follistatin-like serine protease inhibitor region (aa125-168) and a C2-type Ig-like domain (aa172-269). There is one splice variant that shows a 70 aa substitution for aa184-304. Mature human IGFBP-rP10 is 87% aa identical to mouse IGFBP-rP10.
Product Categories/Family for anti-IGFBPL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,005 Da
NCBI Official Full Name
insulin-like growth factor-binding protein-like 1
NCBI Official Synonym Full Names
insulin-like growth factor binding protein-like 1
NCBI Official Symbol
IGFBPL1
NCBI Official Synonym Symbols
IGFBPRP4; IGFBP-RP4; bA113O24.1
NCBI Protein Information
insulin-like growth factor-binding protein-like 1; IGFBP-related protein 10; insulin-like growth factor-binding-related protein 4; insulin-like growth factor binding protein related protein 4
UniProt Protein Name
Insulin-like growth factor-binding protein-like 1
Protein Family
UniProt Gene Name
IGFBPL1
UniProt Synonym Gene Names
IGFBPRP4; IGFBP-rP4
UniProt Entry Name
IBPL1_HUMAN
Uniprot Description
IGFBPL1: IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors. May be a putative tumor suppressor protein.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p13.1
Cellular Component: extracellular region
Molecular Function: insulin-like growth factor binding
Biological Process: regulation of cell growth
Research Articles on IGFBPL1
Similar Products
Product Notes
The IGFBPL1 igfbpl1 (Catalog #AAA627542) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Insulin-Like Growth Factor Binding Protein-Related Protein 10 (IGFBP-rP10, Kazal-type Serine Protease Inhibitor Domain-containing Protein 1, Bone and Odontoblast-expressed Protein 1, Insulin-like Growth Factor-binding-related Protein 10, IGFBP-rP10, IGFBP reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Insulin-Like Growth Factor Binding Protein-Related Protein 10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 0.1-0.2ug/ml, Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the IGFBPL1 igfbpl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Insulin-Like Growth Factor Binding Protein-Related Protein 10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
