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Western Blot (WB)
(Western Blot: Sample: Mouse Serum.)
Rabbit Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Polyclonal Antibody | anti-IGFBP7 antibody
Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 7 (IGFBP7)
Gene Names
Igfbp7; AGM; Fstl2; Mac25
Reactivity
Mus musculus (Mouse)
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Insulin Like Growth Factor Binding Protein 7 (IGFBP7); Polyclonal Antibody; Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 7 (IGFBP7); anti-IGFBP7 antibody
Host
Rabbit
Reactivity
Mus musculus (Mouse)
Clonality
Polyclonal
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
0.85mg/ml (varies by lot)
Applicable Applications for anti-IGFBP7 antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes
Western blotting: 0.5-5ug/mL
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant IGFBP7 (Lys88~Leu281) expressed in E.coli ( MBS2009939 ).
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Mouse Serum.)
Western Blot (WB)
(Western Blot: Sample: Mouse Serum.)
Western Blot (WB)
(Western Blot: Sample: Recombinant IGFBP7, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant IGFBP7, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Brain Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Brain Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Liver Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Liver Tissue.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
insulin-like growth factor-binding protein 7 isoform 2
NCBI Official Synonym Full Names
insulin-like growth factor binding protein 7
NCBI Official Symbol
Igfbp7
NCBI Official Synonym Symbols
AGM; Fstl2; Mac25
NCBI Protein Information
insulin-like growth factor-binding protein 7
UniProt Protein Name
Insulin-like growth factor-binding protein 7
Protein Family
UniProt Gene Name
Igfbp7
UniProt Synonym Gene Names
Mac25; IBP-7; IGF-binding protein 7; IGFBP-7
Uniprot Description
IGFBP7: Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Defects in IGFBP7 are the cause of retinal arterial macroaneurysm with supravalvular pulmonic stenosis (RAMSVPS). RAMSVPS is an autosomal recessive condition characterized by the bilateral appearance of 'beading' along the major retinal arterial trunks, with the subsequent formation of macroaneurysms. Affected individuals also have supravalvular pulmonic stenosis, often requiring surgical correction.
Protein type: Cell adhesion; Cell cycle regulation; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5|5 C3.3
Cellular Component: extracellular matrix; extracellular region; extracellular space
Molecular Function: growth factor binding; insulin-like growth factor binding
Biological Process: cell adhesion; inner ear development; regulation of cell growth; regulation of steroid biosynthetic process
Research Articles on IGFBP7
Similar Products
Product Notes
The IGFBP7 igfbp7 (Catalog #AAA2002807) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 7 (IGFBP7) reacts with Mus musculus (Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Insulin Like Growth Factor Binding Protein 7 (IGFBP7) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-5ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the IGFBP7 igfbp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Insulin Like Growth Factor Binding Protein 7 (IGFBP7), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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