Knockout Validation
(Knockout Validation: Lane 1: Wild-type MCF7 cell lysate; Lane 2: INPP4A knockout MCF7 cell lysate; Predicted MW: 106~110kd Observed MW: 100kd Primary Ab: 1ug/ml Rabbit Anti-Human INPP4A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Rabbit anti-Human Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A) Polyclonal Antibody | anti-INPP4A antibody
FITC-Linked Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A)
Knockout Validation
(Knockout Validation: Lane 1: Wild-type MCF7 cell lysate; Lane 2: INPP4A knockout MCF7 cell lysate; Predicted MW: 106~110kd Observed MW: 100kd Primary Ab: 1ug/ml Rabbit Anti-Human INPP4A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Knockout Validation
(Knockout Validation: Lane 1: Wild-type MCF7 cell lysate; Lane 2: INPP4A knockout MCF7 cell lysate; Predicted MW: 106~110kd Observed MW: 100kd Primary Ab: 1ug/ml Rabbit Anti-Human INPP4A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008]
Uniprot Description
INPP4: inositol polyphosphate 4-phosphatase type I, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.66; Phosphatase, lipid
Chromosomal Location of Human Ortholog: 2q11.2
Cellular Component: cytoplasm; cytosol
Molecular Function: inositol-1,3,4-trisphosphate 4-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; protein binding
Biological Process: inositol phosphate metabolic process; phosphatidylinositol biosynthetic process; signal transduction
Research Articles on INPP4A
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Product Notes
The INPP4A inpp4a (Catalog #AAA2083092) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FITC-Linked Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the INPP4A inpp4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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