Rabbit anti-Human, Mouse IMMP1L Polyclonal Antibody | anti-IMMP1L antibody

IMMP1L, CT (IMMP1L, Mitochondrial inner membrane protease subunit 1, IMP1-like protein)

Cat. Num. AAA6004062

• Gene Names: IMMP1L; IMP1; IMP1-LIKE
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: IMMP1L; Polyclonal Antibody; CT (IMMP1L; Mitochondrial inner membrane protease subunit 1; IMP1-like protein); Anti -IMMP1L; anti-IMMP1L antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-IMMP1L antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: IMMP1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human IMMP1L.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(IMMP1L Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the IMMP1L antibody detected the IMMP1L protein (arrow).)

Related Product Information for anti-IMMP1L antibody

The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).

Product Categories/Family for anti-IMMP1L antibody

Antibodies; Abs to Mitochondrial Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 23270839
• NCBI GeneID: 196294
• UniProt Accession #: Q96LU5; Q96SH9; D3DQZ7
• Molecular Weight: 18,504 Da
• NCBI Official Full Name: IMMP1L protein
• NCBI Official Synonym Full Names: IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
• NCBI Official Symbol: IMMP1L
• NCBI Official Synonym Symbols: IMP1; IMP1-LIKE
• NCBI Protein Information: mitochondrial inner membrane protease subunit 1
• UniProt Protein Name: Mitochondrial inner membrane protease subunit 1
• UniProt Gene Name: IMMP1L
• UniProt Entry Name: IMP1L_HUMAN

NCBI Description

The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008]

Uniprot Description

IMMP1L: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. Belongs to the peptidase S26 family. IMP1 subfamily.

Protein type: Protease; Mitochondrial; EC 3.4.21.-

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: serine-type peptidase activity

Biological Process: mitochondrial protein processing; proteolysis