Testing Data
Rabbit ILP-2 Polyclonal Antibody | anti-ILP-2 antibody
ILP-2 Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
ILP-2; Polyclonal Antibody; ILP-2 Antibody; BIRC8; BIRC 8; BIRC-8; ILP2; hILP2; hILP 2; IAP like protein 2; anti-ILP-2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-ILP-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
236
Applicable Applications for anti-ILP-2 antibody
Western Blot (WB)
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal dilution conditions should be determined individually. The affinity-purified rabbit antibody recognizes ~32 kDa ILP-2 in samples from human, mouse and rat origins.
Immunogen
Synthetic peptide surrounding amino acid 23 of human ILP-2
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-ILP-2 antibody
Background: ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibit apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
27,089 Da
NCBI Official Full Name
IAP-like protein 2
UniProt Protein Name
Baculoviral IAP repeat-containing protein 8
UniProt Gene Name
BIRC8
UniProt Synonym Gene Names
ILP2; IAP-like protein 2; ILP-2
UniProt Entry Name
BIRC8_HUMAN
Uniprot Description
BIRC8: Protects against apoptosis mediated by BAX. Belongs to the IAP family.
Protein type: Apoptosis; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: -
Cellular Component: perinuclear region of cytoplasm; spindle microtubule; cytoplasm; nucleus; cytosol
Molecular Function: protease binding; zinc ion binding; caspase inhibitor activity; ubiquitin-protein ligase activity
Biological Process: neuron apoptosis; protein ubiquitination; negative regulation of neuron apoptosis; negative regulation of apoptosis
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Product Notes
The ILP-2 birc8 (Catalog #AAA840364) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ILP-2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ILP-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (0.5-4 ug/ml). However, the optimal dilution conditions should be determined individually. The affinity-purified rabbit antibody recognizes ~32 kDa ILP-2 in samples from human, mouse and rat origins. Researchers should empirically determine the suitability of the ILP-2 birc8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ILP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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