Rabbit anti-Human IL_6 IL6 Polyclonal Antibody | anti-IL6 antibody
IL6 antibody
Reactivity
Human IL_6
Applications
ELISA, Western Blot
Synonyms
IL6; Polyclonal Antibody; IL6 antibody; Polyclonal IL6; Anti-IL6; 26 kDa; IL 6; IL-6; BSF-2; B cell differentiation factor; Interleukin 6; IFN-beta2; BCDF; MGI-2; HPGF; HSF; anti-IL6 antibody
Host
Rabbit
Reactivity
Human IL_6
Clonality
Polyclonal
Specificity
Human IL_6
Form/Format
Lyophilized from PBS, pH 7.2.
Sequence Length
207
Applicable Applications for anti-IL6 antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
Inhibition: 0.2-0.4 ug/ml
WB: 0.1-0.2 ug/ml
Inhibition: 0.2-0.4 ug/ml
WB: 0.1-0.2 ug/ml
Biological Significance
IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells.
Immunogen
IL6 antibody was raised in rabbit using highly pure recombinant hIL-6 as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-IL6 antibody
Affinity purified Rabbit polyclonal IL6 antibody
Product Categories/Family for anti-IL6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21.7 kDa (predicted detection band MW)
NCBI Official Full Name
interleukin-6
NCBI Official Symbol
IL6
NCBI Protein Information
interleukin-6
UniProt Protein Name
Interleukin-6
Protein Family
UniProt Gene Name
IL6
UniProt Synonym Gene Names
IL-6
UniProt Entry Name
IL6_FELCA
Uniprot Description
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().
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Product Notes
The IL6 il6 (Catalog #AAA534781) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL6 antibody reacts with Human IL_6 and may cross-react with other species as described in the data sheet. AAA Biotech's IL6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). ELISA: 0.5-2 ug/ml Inhibition: 0.2-0.4 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the IL6 il6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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