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Western Blot (WB) (Western Blot analysis of IL31 in Human placenta tissue using IL31 Rabbit pAb at dilution 1/200)

Rabbit anti-Human IL31 Polyclonal Antibody | anti-IL31 antibody

IL31 Rabbit pAb

Gene Names
IL31; IL-31
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
IL31; Polyclonal Antibody; IL31 Rabbit pAb; interleukin 31; IL-31; anti-IL31 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.4mg/ml (varies by lot)
Applicable Applications for anti-IL31 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC-P: 1:25-1:100
Immunogen
Synthetic peptide of human IL31
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of IL31 in Human placenta tissue using IL31 Rabbit pAb at dilution 1/200)

Western Blot (WB) (Western Blot analysis of IL31 in Human placenta tissue using IL31 Rabbit pAb at dilution 1/200)

Immunohistochemistry (IHC)

(Immunohistochemistry of IL31 in paraffin-embedded Human liver cancer tissue using IL31 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)

Immunohistochemistry (IHC) (Immunohistochemistry of IL31 in paraffin-embedded Human liver cancer tissue using IL31 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)
Related Product Information for anti-IL31 antibody
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,205 Da
NCBI Official Full Name
interleukin-31
NCBI Official Synonym Full Names
interleukin 31
NCBI Official Symbol
IL31
NCBI Official Synonym Symbols
IL-31
NCBI Protein Information
interleukin-31
UniProt Protein Name
Interleukin-31
Protein Family
UniProt Gene Name
IL31
UniProt Synonym Gene Names
IL-31
UniProt Entry Name
IL31_HUMAN

NCBI Description

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]

Uniprot Description

IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: immune system process

Research Articles on IL31

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Product Notes

The IL31 il31 (Catalog #AAA4759613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL31 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL31 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the IL31 il31 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL31, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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