Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125814(IL27RA Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))
Rabbit anti-Human, Mouse IL27RA Polyclonal Antibody | anti-IL27RA antibody
IL27RA Antibody
WB: 1:200-1:1000
IHC: 1:50-1:200
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125814(IL27RA Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125814(IL27RA Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7125814(IL27RA Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7125814(IL27RA Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))
SDS-Page
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse thymus tissue, Mouse heart tissue, Primary antibody: MBS7125814(IL27RA Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)
SDS-Page
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse thymus tissue, Mouse heart tissue, Primary antibody: MBS7125814(IL27RA Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)
NCBI and Uniprot Product Information
NCBI Description
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
Uniprot Description
IL27RA: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1- type immune responses. Also appears to be involved in innate defense mechanisms. Belongs to the type I cytokine receptor family. Type 2 subfamily.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component: integral to plasma membrane
Molecular Function: interleukin-27 receptor activity; transmembrane receptor activity
Biological Process: defense response to Gram-positive bacterium; positive regulation of interferon-gamma production; cell surface receptor linked signal transduction; positive regulation of T-helper 1 type immune response; negative regulation of T-helper 2 type immune response; immune response; regulation of isotype switching to IgG isotypes
Research Articles on IL27RA
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Product Notes
The IL27RA il27ra (Catalog #AAA7125814) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL27RA Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL27RA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:200-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the IL27RA il27ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL27RA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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