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Western Blot (WB) (IL22RA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IL22RA1 antibody detected the IL22RA1 protein (arrow).)

Rabbit anti-Human IL22RA1 Polyclonal Antibody | anti-IL22RA1 antibody

IL22RA1, CT (IL22RA1, IL22R, Interleukin-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, ZcytoR11) (PE)

Gene Names
IL22RA1; IL22R; CRF2-9; IL22R1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
IL22RA1; Polyclonal Antibody; CT (IL22RA1; IL22R; Interleukin-22 receptor subunit alpha-1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; ZcytoR11) (PE); ZcytoR11; anti-IL22RA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-IL22RA1 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
IL22RA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of human IL22RA1.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(IL22RA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IL22RA1 antibody detected the IL22RA1 protein (arrow).)

Western Blot (WB) (IL22RA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IL22RA1 antibody detected the IL22RA1 protein (arrow).)
Related Product Information for anti-IL22RA1 antibody
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.
Product Categories/Family for anti-IL22RA1 antibody
References
Meng, S., et al. J Mol Cell Biol 2(4):223-230(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Tohyama, M., et al. Eur. J. Immunol. 39(10):2779-2788(2009). Dumoutier, L., et al. J. Biol. Chem. 284(39):26377-26384(2009). Zhu, H., et al. HBPD INT 8(4):402-406(2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,077 Da
NCBI Official Full Name
interleukin-22 receptor subunit alpha-1
NCBI Official Synonym Full Names
interleukin 22 receptor, alpha 1
NCBI Official Symbol
IL22RA1
NCBI Official Synonym Symbols
IL22R; CRF2-9; IL22R1
NCBI Protein Information
interleukin-22 receptor subunit alpha-1; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9
UniProt Protein Name
Interleukin-22 receptor subunit alpha-1
Protein Family
UniProt Gene Name
IL22RA1
UniProt Synonym Gene Names
IL22R; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1; CRF2-9
UniProt Entry Name
I22R1_HUMAN

NCBI Description

The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]

Uniprot Description

IL22RA1: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: integral to membrane; plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interferon receptor activity; interleukin-20 binding

Biological Process: cytokine and chemokine mediated signaling pathway; defense response to Gram-negative bacterium

Research Articles on IL22RA1

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Product Notes

The IL22RA1 il22ra1 (Catalog #AAA6310101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL22RA1, CT (IL22RA1, IL22R, Interleukin-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, ZcytoR11) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL22RA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the IL22RA1 il22ra1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL22RA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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