Rabbit anti-Human IL20 Polyclonal Antibody | anti-IL20 antibody

IL20 Rabbit Polyclonal

Cat. Num. AAA7600481

• Gene Names: IL20; IL-20; IL10D; ZCYTO10
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: IL20; Polyclonal Antibody; IL20 Rabbit Polyclonal; anti-IL20 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 176

• Applicable Applications for anti-IL20 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Interleukin 20
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS7600481 (IL20 Antibody) at dilution of 1:50)

Western Blot (WB)

(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7600481 (IL20 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 31083166
• NCBI GeneID: 50604
• NCBI Accession #: NP_061194.2
• NCBI GenBank Nucleotide #: NM_018724.3
• Molecular Weight: 17,144 Da
• NCBI Official Full Name: interleukin-20
• NCBI Official Synonym Full Names: interleukin 20
• NCBI Official Symbol: IL20
• NCBI Official Synonym Symbols: IL-20; IL10D; ZCYTO10
• NCBI Protein Information: interleukin-20
• UniProt Protein Name: Interleukin-20
• Protein Family: Interleukin
• UniProt Gene Name: IL20
• UniProt Synonym Gene Names: ZCYTO10; IL-20
• UniProt Entry Name: IL20_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]

Uniprot Description

IL20: Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. Belongs to the IL-10 family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; interleukin-20 receptor binding; interleukin-22 receptor binding

Biological Process: immune response; positive regulation of epidermal cell differentiation; positive regulation of keratinocyte differentiation; positive regulation of osteoclast differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of inflammatory response