Rabbit anti-Human IL18BP Polyclonal Antibody | anti-IL18BP antibody
IL18BP antibody
Reactivity
Human
Applications
Western Blot
Purity
IL18BP antibody was purified by affinity chromatography.
Synonyms
IL18BP; Polyclonal Antibody; IL18BP antibody; Polyclonal IL18BP; Anti-IL18BP; ILBP 18; ILBP-18; IL18 BP; Interleukin 18 Binding Protein; IL-18BP; anti-IL18BP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
IL18BP antibody was purified by affinity chromatography.
Form/Format
Affinity purified IgG supplied in PBS with 0.02% NaN3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
194
Applicable Applications for anti-IL18BP antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1,000
Biological Significance
IL-18 is a cytokine and acts as an early signal in the development of the helper T cell (Th1) response. IL-18BP is a binding protein that binds IL-18 and neutralizes the biological activity of IL-18 in vitro.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
IL18BP antibody was raised in rabbit using residues 44-55 [STKDPCPSQPPVC] of the 40 kDa human IL-18BP as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-IL18BP antibody
Affinity purified Rabbit polyclonal IL18BP antibody
Product Categories/Family for anti-IL18BP antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
17,478 Da
NCBI Official Full Name
interleukin-18 binding protein
UniProt Protein Name
Interleukin-18-binding protein
Protein Family
UniProt Gene Name
IL18BP
UniProt Synonym Gene Names
IL-18BP
UniProt Entry Name
I18BP_HUMAN
Uniprot Description
IL18BP: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: extracellular space; extracellular region
Molecular Function: receptor antagonist activity; interleukin-18 binding
Biological Process: T-helper 1 type immune response; response to lipopolysaccharide
Similar Products
Product Notes
The IL18BP il18bp (Catalog #AAA536264) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL18BP antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL18BP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the IL18BP il18bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL18BP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
