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Western Blot (WB) (Western blot analysis of extracts from PC-3 cells, using IL17RE Antibody. The lane on the left was treated with blocking peptide.)

Rabbit IL17RE Polyclonal Antibody | anti-IL17RE antibody

IL17RE Antibody

Reactivity
Human, Mouse
Predicted: Pig, Rabbit, Dog
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
IL17RE; Polyclonal Antibody; IL17RE Antibody; FLJ23658; IL-17 receptor E; IL-17RE; interleukin 17 receptor E; Interleukin-17 receptor E; MGC71884; OTTHUMP00000158822; UNQ3056/PRO9877; anti-IL17RE antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Predicted: Pig, Rabbit, Dog
Clonality
Polyclonal
Isotype
IgG
Specificity
IL17RE Antibody detects endogenous levels of IL17RE.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
707
Applicable Applications for anti-IL17RE antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human IL17RE.
Tissue Specificity
Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Plasma Membrane; Extracellular Region or Secreted; Extracellular Region or Secreted
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from PC-3 cells, using IL17RE Antibody. The lane on the left was treated with blocking peptide.)

Western Blot (WB) (Western blot analysis of extracts from PC-3 cells, using IL17RE Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-IL17RE antibody
Description: Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2/ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.

Subunit Structure: Forms heterodimers with IL17RA; the heterodimer binds IL17C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 75 kDa
Predicted: 75 kDa
NCBI Official Full Name
interleukin-17 receptor E isoform 5
NCBI Official Synonym Full Names
interleukin 17 receptor E
NCBI Official Symbol
IL17RE
NCBI Protein Information
interleukin-17 receptor E
UniProt Protein Name
Interleukin-17 receptor E
Protein Family
UniProt Gene Name
IL17RE
UniProt Synonym Gene Names
IL-17 receptor E; IL-17RE
UniProt Entry Name
I17RE_HUMAN

NCBI Description

This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]

Uniprot Description

IL17RE: Receptor which can activate the MAPK signaling pathway and seems to function at or upstream of Ras. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: integral to plasma membrane; cytoplasm; extracellular region

Molecular Function: protein binding; interleukin-17 receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway; inflammatory response

Research Articles on IL17RE

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Product Notes

The IL17RE il17re (Catalog #AAA9611837) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL17RE Antibody reacts with Human, Mouse Predicted: Pig, Rabbit, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's IL17RE can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the IL17RE il17re for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17RE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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