Western Blot (WB)
(Western Blot analysis of extracts of various cells, using IL17RB antibody.)
Rabbit IL17RB Polyclonal Antibody | anti-IL17RB antibody
IL17RB Polyclonal Antibody
Gene Names
IL17RB; CRL4; EVI27; IL17BR; IL17RH1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
IL17RB; Polyclonal Antibody; IL17RB Polyclonal Antibody; Interleukin-17 receptor B; IL-17 receptor B; IL-17RB; Cytokine receptor-like 4; IL-17 receptor homolog 1; IL-17Rh1; IL17Rh1; Interleukin-17B receptor; IL-17B receptor; CRL4; EVI27; IL17BR; UNQ2501/PRO19612; anti-IL17RB antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
IL17RB polyclonal antibody detects endogenous levels of IL17RB protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
502
Applicable Applications for anti-IL17RB antibody
Western Blot (WB)
Application Notes
WB: 1:1000-1:4000
Immunogen
Recombinant protein of human IL17RB.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using IL17RB antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using IL17RB antibody.)
Related Product Information for anti-IL17RB antibody
Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. IL-17RB is a member of the cytokine receptor family and acts as a receptor for the proinflammatory cytokines IL-17B and IL-17E. It may play a role in hematopoietic cell differentiation and growth. IL-17RB expression is high in liver, colon, brain, kidney and testis. IL-17RB is detected in fibroblast-like synoviocytes of rheumatoid arthritis patients.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 75kDa
NCBI Official Full Name
interleukin-17 receptor B
NCBI Official Synonym Full Names
interleukin 17 receptor B
NCBI Official Symbol
IL17RB
NCBI Official Synonym Symbols
CRL4; EVI27; IL17BR; IL17RH1
NCBI Protein Information
interleukin-17 receptor B
UniProt Protein Name
Interleukin-17 receptor B
Protein Family
UniProt Gene Name
IL17RB
UniProt Synonym Gene Names
CRL4; EVI27; IL17BR; IL-17 receptor B; IL-17RB; IL-17Rh1; IL17Rh1; IL-17B receptor
UniProt Entry Name
I17RB_HUMAN
NCBI Description
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
IL17RB: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: interleukin-17 receptor activity
Biological Process: defense response
Research Articles on IL17RB
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Product Notes
The IL17RB il17rb (Catalog #AAA3008867) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL17RB Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IL17RB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-1:4000. Researchers should empirically determine the suitability of the IL17RB il17rb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17RB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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