Rabbit anti-Human, mouse IL17B Polyclonal Antibody | anti-IL17B antibody
IL17B Antibody (Center)
Western Blot (WB)
(IL17B Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the IL17B antibody detected the IL17B protein (arrow).)
Western Blot (WB)
(Western blot analysis of IL17B (arrow) using rabbit polyclonal IL17B Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IL17B gene.)
Immunohistochemistry (IHC)
(IL17B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL17B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunofluorescence (IF)
(Confocal immunofluorescent analysis of IL17B Antibody (Center) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
cytokine that shares sequence similarity with IL17. This cytokine
was reported to stimulate the release of TNF alpha (TNF) and IL1
beta (IL1B) from a monocytic cell line. Immunohistochemical
analysis of several nerve tissues indicated that this cytokine is
primarily localized to neuronal cell bodies.
Wang, X., et al. Ann. Otol. Rhinol. Laryngol. 115(6):450-456(2006)
Ryan, A.W., et al. Tissue Antigens 65(2):150-155(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Moore, E.E., et al. Neuromuscul. Disord. 12(2):141-150(2002)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq, Jul 2008]
Uniprot Description
IL17B: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Belongs to the IL-17 family.
Protein type: Secreted, signal peptide; Secreted; Cytokine
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: cell-cell signaling; immune response; inflammatory response
Research Articles on IL17B
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Product Notes
The IL17B il17b (Catalog #AAA9211890) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 39-66. The IL17B Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL17B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). WB~~1:1000. Researchers should empirically determine the suitability of the IL17B il17b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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