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Immunohistochemistry (IHC) (Anti-IL13RA1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit IL13RA1 / IL13R Alpha 1 Polyclonal Antibody | anti-IL13RA1 / IL13R Alpha 1 antibody

Anti-IL13RA1 / IL13R Alpha 1 Antibody (Lys401) IHC-plus

Gene Names
IL13RA1; NR4; CT19; CD213A1; IL-13Ra
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot
Purity
Immunoaffinity purified
Synonyms
IL13RA1 / IL13R Alpha 1; Polyclonal Antibody; Anti-IL13RA1 / IL13R Alpha 1 Antibody (Lys401) IHC-plus; Rabbit Polyclonal to Human IL13RA1 / IL13R Alpha 1; Human IL13RA1 / IL13R Alpha 1; Cancer/testis antigen 19; CD213A1; CD213a1 antigen; CT19; IL-13R-alpha-1; NR4; IL-13R subunit alpha-1; IL-13Ra; IL-13RA1; IL13R; IL13RA; IL-13 receptor subunit alpha-1; IL13 receptor alpha-1 chain; anti-IL13RA1 / IL13R Alpha 1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
Human IL13RA1 / IL13R
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH 7.2, 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
427
Applicable Applications for anti-IL13RA1 / IL13R Alpha 1 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB)
Application Notes
IF (1:50 - 1:200)
IHC-P (5 ug/ml)
WB (1:500 - 1:1000)
Immunogen
IL13RA1 / IL13R Alpha 1 antibody was raised against synthetic peptide around Lys401 of human IL13RA1 / IL13R
Immunogen Description
Synthetic peptide around Lys401 of human IL13RA1 / IL13R
Immunogen Type
Synthetic peptide
Antigen Modification
Lys401
Target Species
Human
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-IL13RA1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-IL13RA1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of IL-13R1 (K401) pAb in extracts from COLO cells.)

Western Blot (WB) (Western blot of IL-13R1 (K401) pAb in extracts from COLO cells.)
Related Product Information for anti-IL13RA1 / IL13R Alpha 1 antibody
IL13RA1 Antibody, Cancer/testis antigen 19 Antibody, CD213A1 Antibody, CD213a1 antigen Antibody, CT19 Antibody, IL-13R-alpha-1 Antibody, NR4 Antibody, IL-13R subunit alpha-1 Antibody, IL-13Ra Antibody, IL-13RA1 Antibody, IL13R Antibody, IL13RA Antibody, IL-13 receptor subunit alpha-1 Antibody, IL13 receptor alpha-1 chain Antibody Description: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,659 Da
NCBI Official Full Name
interleukin-13 receptor subunit alpha-1
NCBI Official Synonym Full Names
interleukin 13 receptor subunit alpha 1
NCBI Official Symbol
IL13RA1
NCBI Official Synonym Symbols
NR4; CT19; CD213A1; IL-13Ra
NCBI Protein Information
interleukin-13 receptor subunit alpha-1
UniProt Protein Name
Interleukin-13 receptor subunit alpha-1
UniProt Gene Name
IL13RA1
UniProt Synonym Gene Names
IL13R; IL13RA; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19
UniProt Entry Name
I13R1_HUMAN

NCBI Description

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

Uniprot Description

IL13R: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. Belongs to the type I cytokine receptor family. Type 5 subfamily.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: interleukin-13 receptor complex; plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding

Biological Process: cell surface receptor linked signal transduction; cytokine and chemokine mediated signaling pathway

Research Articles on IL13RA1 / IL13R Alpha 1

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Product Notes

The IL13RA1 / IL13R Alpha 1 il13ra1 (Catalog #AAA2400015) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL13RA1 / IL13R Alpha 1 Antibody (Lys401) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL13RA1 / IL13R Alpha 1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB). IF (1:50 - 1:200) IHC-P (5 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the IL13RA1 / IL13R Alpha 1 il13ra1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL13RA1 / IL13R Alpha 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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