Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat kidney using IL12RB1 Polyclonal Antibody at dilution of 1:200 (40x lens).)
Rabbit anti-Human, Rat IL12RB1 Polyclonal Antibody | anti-IL12RB1 antibody
IL12RB1 Polyclonal Antibody
Gene Names
IL12RB1; CD212; IMD30; IL12RB; IL-12R-BETA1
Reactivity
Human, Rat
Applications
Immunohistochemistry, Immunofluorescence
Purity
Affinity purification
Synonyms
IL12RB1; Polyclonal Antibody; IL12RB1 Polyclonal Antibody; CD212; IL-12R-BETA1; IL12RB; IMD30; anti-IL12RB1 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-IL12RB1 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:50-1:200
IF: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant fusion protein of human IL12RB1 (NP_7149121)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat kidney using IL12RB1 Polyclonal Antibody at dilution of 1:200 (40x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat kidney using IL12RB1 Polyclonal Antibody at dilution of 1:200 (40x lens).)
Immunofluorescence (IF)
(Immunofluorescence analysis of MCF7 cells using IL12RB1 Polyclonal Antibody )
Immunofluorescence (IF)
(Immunofluorescence analysis of MCF7 cells using IL12RB1 Polyclonal Antibody )
Related Product Information for anti-IL12RB1 antibody
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-IL12RB1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,366 Da
NCBI Official Full Name
interleukin-12 receptor subunit beta-1 isoform 3
NCBI Official Synonym Full Names
interleukin 12 receptor subunit beta 1
NCBI Official Symbol
IL12RB1
NCBI Official Synonym Symbols
CD212; IMD30; IL12RB; IL-12R-BETA1
NCBI Protein Information
interleukin-12 receptor subunit beta-1
UniProt Protein Name
Interleukin-12 receptor subunit beta-1
Protein Family
UniProt Gene Name
IL12RB1
UniProt Synonym Gene Names
IL12R; IL12RB; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1
UniProt Entry Name
I12R1_HUMAN
Uniprot Description
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Similar Products
Product Notes
The IL12RB1 il12rb1 (Catalog #AAA2564881) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL12RB1 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IL12RB1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the IL12RB1 il12rb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL12RB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
