Rabbit IL1 alpha Polyclonal Antibody | anti-IL1 alpha antibody
IL1 alpha antibody
Gene Names
IL1A; IL-1alpha
Reactivity
Human IL-1 alpha
Applications
ELISA, Western Blot
Synonyms
IL1 alpha; Polyclonal Antibody; IL1 alpha antibody; Polyclonal IL1 alpha; Anti-IL1 alpha; Mononuclear Cell Factor; IL-1 alpha; Interleukin 1 alpha; MCF; LAF; EP; Lymphocyte-activating factor; Leukocyte Endogenous Mediator; Hematopoietin-1; Endogenous Pyrogen; LEM; anti-IL1 alpha antibody
Host
Rabbit
Reactivity
Human IL-1 alpha
Clonality
Polyclonal
Specificity
Human IL-1 alpha
Form/Format
Lyophilized from PBS, pH 7.2. Reconstitute in sterile water at a concentration of >0.2 mg/ml.
Sequence Length
270
Applicable Applications for anti-IL1 alpha antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
Inhibition: 1-2 ug/ml
WB: 0.1-0.2 ug/ml
Inhibition: 1-2 ug/ml
WB: 0.1-0.2 ug/ml
Biological Significance
IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
Immunogen
IL1 alpha antibody was raised in rabbit using highly pure recombinant human IL-1-alpha as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-IL1 alpha antibody
Affinity purified Rabbit polyclonal IL1 alpha antibody
Product Categories/Family for anti-IL1 alpha antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17.7 kDa (predicted detection band MW)
NCBI Official Full Name
interleukin-1 alpha
NCBI Official Symbol
IL1A
NCBI Official Synonym Symbols
IL-1alpha
NCBI Protein Information
interleukin-1 alpha
UniProt Protein Name
Interleukin-1 alpha
UniProt Gene Name
IL1A
UniProt Synonym Gene Names
IL-1 alpha
UniProt Entry Name
IL1A_PIG
Uniprot Description
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Research Articles on IL1 alpha
Similar Products
Product Notes
The IL1 alpha il1a (Catalog #AAA535124) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL1 alpha antibody reacts with Human IL-1 alpha and may cross-react with other species as described in the data sheet. AAA Biotech's IL1 alpha can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). ELISA: 0.5-2 ug/ml Inhibition: 1-2 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the IL1 alpha il1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL1 alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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