Western Blot (WB)
(Western Blot (WB) analysis of IKZF2 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug))
Rabbit IKZF2 Polyclonal Antibody | anti-IKZF2 antibody
IKZF2 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
IKZF2; Polyclonal Antibody; IKZF2 Polyclonal Antibody; Zinc finger protein Helios; Ikaros family zinc finger protein 2; HELIOS; ZNFN1A2; anti-IKZF2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
IKZF2 polyclonal antibody detects endogenous levels of IKZF2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
500
Applicable Applications for anti-IKZF2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding Human IKZF2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of IKZF2 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of IKZF2 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug))
Related Product Information for anti-IKZF2 antibody
Helios (Ikaros family zinc finger 2, IZKF2) is an Ikaros family transcription factor composed of several zinc fingers that mediate DNA binding and homodimerization or heterodimerization with other Ikaros family proteins. In the hematopoietic system, Helios expression is restricted to T cells and early hematopoietic progenitors. In regulatory T cells, expression of Helios contributes to an anergic phenotype by binding to the IL-2 promoter and suppressing IL-2 transcription. In addition, alteration of the corresponding Helios gene IZKF2 is one hallmark of low-hypodiploid acute lymphoblastic leukemia.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 85kDa
NCBI Official Full Name
zinc finger protein Helios isoform 2
UniProt Protein Name
Zinc finger protein Helios
Protein Family
UniProt Gene Name
IKZF2
UniProt Synonym Gene Names
HELIOS; ZNFN1A2
UniProt Entry Name
IKZF2_HUMAN
Uniprot Description
Helios: Associates with Ikaros at centromeric heterochromatin. Belongs to the Ikaros C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 2q34
Cellular Component: nucleus
Molecular Function: protein binding; protein homodimerization activity; DNA binding; protein heterodimerization activity; metal ion binding
Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
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Product Notes
The IKZF2 ikzf2 (Catalog #AAA3007554) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKZF2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IKZF2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the IKZF2 ikzf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKZF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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