Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IKK alpha antibody (Ser180/181))
Rabbit IKK Alpha Polyclonal Antibody | anti-IKKA antibody
IKK Alpha Antibody (Ser180/181)
Gene Names
CHUK; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
Applications
Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
IKK Alpha; Polyclonal Antibody; IKK Alpha Antibody (Ser180/181); Rabbit Polyclonal IKK alpha Antibody (Ser180/181); Polyclonal IKK alpha antibody; Anti-IKK alpha antibody; CHUK antibody; conserved helix-loop ubiquitous kinase antibody; Conserved helix-loop-helix ubiquitous kinase antibody; I-kappa-B kinase 1 antibody; I-kappa-B kinase alpha antibody; I-kappa-B kinase-alpha antibody; IkappaB kinase antibody; IkB kinase alpha subunit antibody; IkBKA antibody; IKK-A antibody; IKK-a kinase antibody; IKK-alpha antibody; IKK1 antibody; IKKA antibody; Inhibitor of nuclear factor kappa-B kinase subunit alpha antibody; NFKBIKA antibody; Nuclear factor NF-kappa-B inhibitor kinase alpha antibody; Nuclear factor NFkappaB inhibitor kinase alpha antibody; TCF-16 antibody; TCF16 antibody; Transcription factor 16 antibody; anti-IKKA antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
IKK alpha antibody (Ser180/181) detects endogenous levels of IKKa/Ikkb onlywhen phosphorylated at Serine 180/181
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
745
Applicable Applications for anti-IKKA antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-100
Immunogen
IKK alpha antibody was raised in Rabbit using a synthesized phosphopeptide derived from human IKKa/Ikkb around the phosphorylation site of Serine 180/181 (C-T-SP-F-V) as the immunogen.
Cross-Reactivity
Mouse
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IKK alpha antibody (Ser180/181))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IKK alpha antibody (Ser180/181))
Related Product Information for anti-IKKA antibody
IKK alpha phosphorylates inhibitors of NF-kappa-B, leading to their dissociation from NF-kappa-B and ultimately to their degradation.
Product Categories/Family for anti-IKKA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1
NCBI Official Synonym Full Names
component of inhibitor of nuclear factor kappa B kinase complex
NCBI Official Symbol
CHUK
NCBI Official Synonym Symbols
IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase subunit alpha
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit alpha
UniProt Gene Name
CHUK
UniProt Synonym Gene Names
IKKA; TCF16; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA; TCF-16
UniProt Entry Name
IKKA_HUMAN
NCBI Description
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
Research Articles on IKKA
Similar Products
Product Notes
The IKKA chuk (Catalog #AAA5313743) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IKK Alpha can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-100. Researchers should empirically determine the suitability of the IKKA chuk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKK Alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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