Western Blot (WB)
(Western blot analysis of IKB alpha expression in THP1 (A); HeLa (B); Raw264.7 (C) whole cell lysates.)
Rabbit IKB Alpha Polyclonal Antibody | anti-IKBA antibody
IKB Alpha Antibody
Gene Names
CHUK; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Purity
Immunogen Affinity Chromatography
Synonyms
IKB Alpha; Polyclonal Antibody; IKB Alpha Antibody; Purified Polyclonal IKB alpha Antibody; Polyclonal IKB alpha antibody; Anti-IKB alpha antibody; IKBA antibody; MAD3 antibody; NFKBI antibody; NF-kappa-B inhibitor alpha antibody; I-kappa-B-alpha antibody; IkB-alpha antibody; IkappaBalpha antibody; Major histocompatibility complex enhancer-binding protein MAD3 antibody; anti-IKBA antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of IKB alpha protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
745
Applicable Applications for anti-IKBA antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
IF: 1:100-1:500
ICC: 1:100-1:500
IP: 1:10-1:100
IHC: 1:100-1:200
IF: 1:100-1:500
ICC: 1:100-1:500
IP: 1:10-1:100
Immunogen
IKB alpha antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IKB alpha as the immunogen
Cross-Reactivity
Mouse, Bovine, Monkey, Pig, Sheep
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of IKB alpha expression in THP1 (A); HeLa (B); Raw264.7 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of IKB alpha expression in THP1 (A); HeLa (B); Raw264.7 (C) whole cell lysates.)
Related Product Information for anti-IKBA antibody
IKB alpha inhibits NF-?B by masking the nuclear localization signals (NLS) of NF-?B proteins and keeping them sequestered in an inactive state in the cytoplasm.
Product Categories/Family for anti-IKBA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1
NCBI Official Synonym Full Names
component of inhibitor of nuclear factor kappa B kinase complex
NCBI Official Symbol
CHUK
NCBI Official Synonym Symbols
IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase subunit alpha
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit alpha
UniProt Gene Name
CHUK
UniProt Synonym Gene Names
IKKA; TCF16; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA; TCF-16
UniProt Entry Name
IKKA_HUMAN
NCBI Description
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
Research Articles on IKBA
Similar Products
Product Notes
The IKBA chuk (Catalog #AAA5314744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IKB Alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 1:500-1:1000 IHC: 1:100-1:200 IF: 1:100-1:500 ICC: 1:100-1:500 IP: 1:10-1:100. Researchers should empirically determine the suitability of the IKBA chuk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKB Alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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