Immunohistochemistry (IHC)
(Anti-CADM4 / NECL-4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit IGSF4C / CADM4 Polyclonal Antibody | anti-IGSF4C antibody
Rabbit Polyclonal to Human IGSF4C / CADM4
Gene Names
CADM4; NECL4; TSLL2; IGSF4C; Necl-4; synCAM4
Reactivity
Bat, Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
IGSF4C / CADM4; Polyclonal Antibody; Rabbit Polyclonal to Human IGSF4C / CADM4; Anti-IGSF4C / CADM4 Antibody (Internal) IHC-plus; CADM4; Cell adhesion molecule 4; Nectin-like 4; Nectin-like protein 4; Necl-4; NECL4; IGSF4C; TSLC1-like 2; SynCAM4; TSLC1-like protein 2; TSLL2; Human IGSF4C; anti-IGSF4C antibody
Host
Rabbit
Reactivity
Bat, Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Clonality
Polyclonal
Specificity
Human CADM4 / NECL-4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
0.8 mg/ml (varies by lot)
Sequence Length
388
Applicable Applications for anti-IGSF4C antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 - 15 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 14 amino acid peptide from internal region of human CADM4 / NECL-4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig, Opossum.
Immunogen Type
Synthetic peptide
Immunogen
IGSF4C / CADM4 antibody was raised against synthetic 14 amino acid peptide from internal region of human CADM4 / NECL-4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig, Opossum, Platypus (100%).
Antigen Modification
Internal
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-CADM4 / NECL-4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-CADM4 / NECL-4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-CADM4 / NECL-4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-CADM4 / NECL-4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-IGSF4C antibody
IGSF4C/TSLL2 is a membrane glycoprotein that along with TSLL1 and TSLC1 form a unique subfamily within the immunoglobulin superfamily. TSLL2 has been shown to be lost in prostate carcinomas and gliomas, suggesting that it may play a role in tumor suppression in addition to cell-cell interaction.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,785 Da
NCBI Official Full Name
cell adhesion molecule 4
NCBI Official Synonym Full Names
cell adhesion molecule 4
NCBI Official Symbol
CADM4
NCBI Official Synonym Symbols
NECL4; TSLL2; IGSF4C; Necl-4; synCAM4
NCBI Protein Information
cell adhesion molecule 4; TSLC1-like 2; nectin-like 4; TSLC1-like protein 2; nectin-like protein 4; immunoglobulin superfamily member 4C; immunoglobulin superfamily, member 4C
UniProt Protein Name
Cell adhesion molecule 4
UniProt Gene Name
CADM4
UniProt Synonym Gene Names
IGSF4C; NECL4; TSLL2; IgSF4C; NECL-4
UniProt Entry Name
CADM4_HUMAN
Uniprot Description
CADM4: Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity. Belongs to the nectin family.
Protein type: Tumor suppressor; Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 19q13.31
Cellular Component: integral to membrane
Biological Process: cell adhesion
Research Articles on IGSF4C
Similar Products
Product Notes
The IGSF4C cadm4 (Catalog #AAA247727) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human IGSF4C / CADM4 reacts with Bat, Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IGSF4C / CADM4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 - 15 ug/ml). Researchers should empirically determine the suitability of the IGSF4C cadm4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGSF4C / CADM4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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