Rabbit IFN ALPHA Polyclonal Antibody | anti-IFNA3 antibody
RABBIT ANTI CHICKEN INTERFERON ALPHA:Preservative Free
Gene Names
IFNA3; IFNA; IFNA1; IFNA2; IFNA6; IFN-alpha; IFN-gamma
Applications
ELISA, Functional Assay, Immunoprecipitation, Western Blot
Synonyms
IFN ALPHA; Polyclonal Antibody; RABBIT ANTI CHICKEN INTERFERON ALPHA:Preservative Free; anti-IFNA3 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
This item recognizes chicken Interferon alpha (chIFNalpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. This item cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma. In bioassays, this antiserum neutralizes chIFN-alpha, but not chIFN-beta, and can therefore be used to discriminate IFN alpha and IFN beta bioactivities, see Schwarz, H. et al. for details.
Form/Format
Preservative Free
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 0.5 mg/ml (varies by lot)
Sequence Length
193
Applicable Applications for anti-IFNA3 antibody
ELISA (EIA), Functional Assays (FN), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Western Blot: This item detects a band of approximately 19kDa.
Immunogen
Recombinant chicken IFN alpha (PAP004)
Buffer Solution
Buffer Solution
Antiserum Preparation
Antisera to chicken Interferon alpha were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G.
Target Species
Chicken
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-IFNA3 antibody
MBS220074 recognizes chicken Interferon alpha (chIFNalpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. MBS220074 cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma. In bioassays, this antiserum neutralizes chIFN-alpha, but not chIFN-beta, and can therefore be used to discriminate IFN alpha and IFN beta bioactivities, see Schwarz, H. et al. for details.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,116 Da
NCBI Official Full Name
interferon type A1/A2
NCBI Official Synonym Full Names
interferon
NCBI Official Symbol
IFNA3
NCBI Official Synonym Symbols
IFNA; IFNA1; IFNA2; IFNA6; IFN-alpha; IFN-gamma
NCBI Protein Information
interferon type A1/A2; IFN alpha; interferon alpha; interferon type A3; interferon-alpha
UniProt Protein Name
Interferon type A1/A2
Protein Family
UniProt Gene Name
IFNA1
UniProt Entry Name
IFNA1_CHICK
Uniprot Description
Has antiviral activities.
Research Articles on IFNA3
Similar Products
Product Notes
The IFNA3 ifna1 (Catalog #AAA220074) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IFN ALPHA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Functional Assays (FN), Immunoprecipitation (IP), Western Blot (WB). Western Blot: This item detects a band of approximately 19kDa. Researchers should empirically determine the suitability of the IFNA3 ifna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFN ALPHA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
