Testing Data
Rabbit anti-Human IFN-alpha 2a Polyclonal Antibody | anti-IFN-alpha 2a antibody
IFN-alpha 2a Antibody
30 ug (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA; 0.01 % thimerosal; and 50 % glycerol.
The antibody solution should be gently mixed before use.
Testing Data
Testing Data
Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens. They belong to the large class of glycoproteins known as cytokines. IFN-alpha is produced by macrophages and has antiviral activities. IFNs also have other functions: they activate immune cells; such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
Uniprot Description
IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family.
Protein type: Membrane protein, integral; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p21.3
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity; interferon-alpha/beta receptor binding; protein binding
Biological Process: apoptosis; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor linked signal transduction; cell-cell signaling; cytokine and chemokine mediated signaling pathway; defense response to virus; humoral immune response; inflammatory response; innate immune response; natural killer cell activation during immune response; negative regulation of T cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of virion penetration into host cell; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of phosphorylation; positive regulation of transcription, DNA-dependent; positive regulation of tyrosine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response
Research Articles on IFN-alpha 2a
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Product Notes
The IFN-alpha 2a ifna2 (Catalog #AAA845514) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IFN-alpha 2a Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IFN-alpha 2a can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1-4 ug. Researchers should empirically determine the suitability of the IFN-alpha 2a ifna2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFN-alpha 2a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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