Western Blot (WB)
(Western blot analysis of extracts from 293, using IBP4 Antibody. Lane 1 was treated with the blocking peptide.)
Rabbit anti-Human IBP4 Polyclonal Antibody | anti-IBP4 antibody
IBP4 Antibody
Gene Names
IGFBP4; BP-4; IBP4; IGFBP-4; HT29-IGFBP
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
IBP4; Polyclonal Antibody; IBP4 Antibody; AI875747; BP 4; BP4; Deb2; HT29 IGFBP; IBP 4; IBP-4; IBP4_HUMAN; IGF binding protein 4; IGF-binding protein 4; IGF-BP4; IGFBP 4; IGFBP-4; IGFBP4; Insulin Like Growth Factor Binding Protein 4; Insulin-like growth factor-binding protein 4; anti-IBP4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
IBP4 antibody detects endogenous levels of total IBP4
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
258
Applicable Applications for anti-IBP4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human IBP4
Subcellular Location
Secreted.
Tissue Specificity
By forskolin and N6, O2'dibutyryl adenosine 3', 5'-cyclic monophosphate, but not by 1, 9 dideoxyforskolin.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%), Xenopus (91%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of extracts from 293, using IBP4 Antibody. Lane 1 was treated with the blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from 293, using IBP4 Antibody. Lane 1 was treated with the blocking peptide.)
Western Blot (WB)
(Western blot analysis IBP4 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis IBP4 using K562 whole cell lysates)
Related Product Information for anti-IBP4 antibody
Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subunit Structure: Binds IGF2 more than IGF1.
Subunit Structure: Binds IGF2 more than IGF1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 28 kDa
Predicted: 28 kDa
Predicted: 28 kDa
NCBI Official Full Name
insulin-like growth factor-binding protein 4
NCBI Official Synonym Full Names
insulin like growth factor binding protein 4
NCBI Official Symbol
IGFBP4
NCBI Official Synonym Symbols
BP-4; IBP4; IGFBP-4; HT29-IGFBP
NCBI Protein Information
insulin-like growth factor-binding protein 4
UniProt Protein Name
Insulin-like growth factor-binding protein 4
UniProt Gene Name
IGFBP4
UniProt Synonym Gene Names
IBP4; IBP-4; IGF-binding protein 4; IGFBP-4
NCBI Description
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]
Uniprot Description
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Research Articles on IBP4
Similar Products
Product Notes
The IBP4 igfbp4 (Catalog #AAA9609275) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IBP4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IBP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the IBP4 igfbp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IBP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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