Western Blot (WB)
(Western blot analysis of anti-IARS2 Antibody (Center) in 293 cell line lysates (35ug/lane).IARS2 (arrow) was detected using the purified Pab.)
Rabbit anti-Human IARS2 Polyclonal Antibody | anti-IARS2 antibody
IARS2 (Isoleucyl-tRNA Synthetase 2 Mitochondrial, IleRS, FLJ10326, Isoleucine-tRNA Ligase) (MaxLight 490)
FLISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of anti-IARS2 Antibody (Center) in 293 cell line lysates (35ug/lane).IARS2 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-IARS2 Antibody (Center) in 293 cell line lysates (35ug/lane).IARS2 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with IARS2 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with IARS2 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014]
Uniprot Description
IARS2: Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein type: Ligase; EC 6.1.1.5; Mitochondrial; Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis
Chromosomal Location of Human Ortholog: 1q41
Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm; cytosol
Molecular Function: ATP binding; isoleucine-tRNA ligase activity
Biological Process: isoleucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; mitochondrial translation; regulation of translational fidelity; gene expression
Disease: Cataracts, Growth Hormone Deficiency, Sensory Neuropathy, Sensorineural Hearing Loss, And Skeletal Dysplasia
Research Articles on IARS2
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Product Notes
The IARS2 iars2 (Catalog #AAA6481355) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IARS2 (Isoleucyl-tRNA Synthetase 2 Mitochondrial, IleRS, FLJ10326, Isoleucine-tRNA Ligase) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IARS2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-1:50 FLISA: 1:1,000 WB: 1:50-1:100 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the IARS2 iars2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IARS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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